低强度红激光延缓近视临床实验分析

The Analysis of Clinical Trial of Slowing the Progression of Myopia in Children with Low Red Laser

为了研究低强度红色激光能否有效控制近视儿童眼轴的延长,将50个8~12岁双眼近视的儿童随机分为框架眼镜联合红光组和框架眼镜对照组进行实验,3个月、6个月后随访眼轴长度、前房深度、角膜曲率、脉络膜厚度及屈光度。结果显示,红光组3个月和6个月后眼轴相对基线分别有82.5%和72.7%的近视右眼无轴性延长,而对照组近视眼100%右眼轴延长,红光组和对照组存在显著差异(p<0.0001),低强度红激光治疗有效延缓轴性近视进展。但是其他生物学参数,比如脉络膜厚度、前房深度、角膜曲率等均无统计学意义上的差别。

The purpose of this study was to quantify the effectiveness of low-lever red laser(LLRDL)in slowing the progression of myopia axial length elongation.Myopic children aged 8 to 12 years were enrolled in a year(with follow-ups at 3 month and 6 month),single-masked,randomized clinical trial.Subjects in each group were randomized to either a LLRDL(test)group or single vision spectacles(control)group.This study was to assess the changing values from 3 and 6 month follow-ups from the baseline,especially the axial length.After 3 months and 6 months,82.5%and 72.7%of myopic eyes of the subjects enrolled had no axial elongation compared with baseline,while the control group had 100%axial elongation,and there were significant differences between red light treatment group and control group(p<0.0001).LLRDL had significant efficacy in control axial elongation.But there were no significant difference between chamber depth,cornea power or choroidal thickness.