磁共振Dixon技术评估绝经后女性第12胸椎骨质疏松的定量研究

目的探讨磁共振Dixon成像技术评估绝经后女性第12胸椎椎体的脂肪含量以及是否出现骨质疏松的应用价值。方法收集绝经后女性第12胸椎椎体102例,通过定量CT(QCT)检查测定骨密度值(BMD),分为骨量正常组及低骨量组,利用磁共振Dixon成像技术参照QCT椎体感兴趣区计算脂肪分数(FF),比较两组的FF值。结果骨量正常组的第12胸椎椎体的BMD值为(142.9±33.6)mg/cm^(3),明显高于低骨量组(73.8±31.4)/cm^(3),FH直为(67.5±5.7)%明显低于低骨量组(81.2±5.3)%,BMD值、FF值的组间差异均有统计学意义(P<0.05)。结论磁共振Dixon成像技术评价绝经后女性第12胸椎椎体骨质疏松的效能与和QCT相当,且具有无辐射损害的优势。

Objective To explore the application value of magnetic resonance Dixon imaging technique in evaluating the fat content of thoracic 12 vertebrae in postmenopausal women and to evaluate the possibility of osteoporosis.Methods 102 postmenopausal women with 12 thoracic vertebrae were collected and their bone mineral density was measured by quantitative CT(QCT)examination.They were divided into the normal bone mass group and the low bone mass group.Dixon imaging technique was used to calculate fat fraction(FF)with reference to QCT vertebral area of interest,and FF values of the two groups were compared.Results The BMD value of the 12th thoracic vertebra in the normal bone mass group was(142.9±33.6)mg/cm^(3),which was significantly higher than that in the low bone mass group(73.8±31.4)mg/cm^(3),and the FF value was(67.5±5.7)%,which was significantly lower than that in the low bone mass group(81.2±5.3)%.There were significant differences in BMD value and FF value between groups(P<0.05).Conclusion Dixon imaging has the same efficacy as QCT in evaluating osteoporosis of the 12th thoracic vertebra in postmenopausal women,and has the advantage of no radiation damage.