胎儿外科研究进展

Research progress of fetal surgery

随着产前诊断技术的快速发展,对胎儿先天畸形认识的不断加深,使得部分宫内发育异常的胎儿可较早得以诊断,并通过胎儿外科(fetal surgery)技术在胎儿期进行干预,可显著改善出生缺陷儿预后,提高远期生存质量。胎儿围产期干预技术在我国发展较晚,虽然胎儿宫内治疗在临床上已逐渐开展应用起来,但由于技术难度、地域人文、经济水平等条件的限制,胎儿围产期外科治疗技术尚难以在全国范围内推广和普及。本文通过回顾国内外胎儿外科治疗的现状及新的研究成果做一综述。

With the rapid development of prenatal diagnosis technology and the deepening understanding of fetal congenital anomalies,some fetuses with abnormal intrauterine developmental can be diagnosed earlier,and interventions can be performed in the fetal period through fetal surgery technology,which can significantly improve the prognosis of children with birth defects and improve the quality of long-term survival.Although intrauterine fetal treatment has been gradually applied in clinical practice,it is difficult to promote and popularize fetal perinatal surgery in China due to the limitations of technical difficulty,regional culture,and economic level.This article reviews the current situation and new research achievements of fetal surgical treatment at home and abroad.