奥扎格雷钠联合银杏达莫注射液治疗急性脑梗死患者的临床效果

Clinical Effect of the Treatment of Acute Cerebral Infarction with Ozagrel Sodium and Gingko Damo Injection

目的分析脑梗死疾病的特点,评价奥扎格雷钠、银杏达莫注射液联合治疗急性脑梗死的临床可行性与整体效果,为急性脑梗死患者的治疗提供参考。方法选择医院2018年2月至2019年7月收治住院治疗的急性脑梗死患者76例。按照随机数表法进行分组治疗,即试验1组与试验2组。试验1组38例患者采取奥扎格雷钠治疗,试验2组38例患者采取奥扎格雷钠联合银杏达莫注射液治疗。比较试验1组与试验2组急性脑梗死患者治疗情况,即神经功能缺损程度、治疗效果、实验室检测结果,以美国国立卫生院神经功能缺损量表(NIHSS)评估两组患者的神经功能缺损程度。结果治疗后,试验2组急性脑梗死患者神经功能缺损程度评分较治疗前下降,且低于试验1组,差异有统计学意义(P<0.05);试验2组急性脑梗死患者治疗总有效率优于试验1组,差异有统计学意义(P<0.05);治疗后,两组患者血浆黏度、全血高切黏度、全血低切黏度实验室检测结果较治疗前下降,且试验2组低于试验1组,差异有统计学意义(P<0.05)。结论奥扎格雷钠联合银杏达莫注射液治疗可进一步提高急性脑梗死患者的治疗效果,降低血黏度,促进患者神经功能的改善。

Objective To analyze the characteristics of cerebral infarction,evaluate the clinical feasibility and overall effect of ozagrel sodium and ginkgo damol injection in the treatment of acute cerebral infarction,and to provide references for the treatment of patients with acute cerebral infarction.Methods A total of 76 patients with acute cerebral infarction who were hospitalized in our hospital from February 2018 to July 2019 were selected.Group treatment was carried out according to the random number table method,namely test group 1 and test group 2,reviewed and approved by the ethics committee,38 patients in test group 1 were treated with ozagrel sodium,and 38 patients in test group 2 were treated with ozagrel sodium combined with ginkgo damo injection.Comparison of the treatment of patients with acute cerebral infarction in test group 1 and test group 2,that is,the degree of neurological impairment,treatment effect,and laboratory test results,the degree of neurological deficit of the patien was assessed by the National Institutes of Health Neurological Impairment Score(NIHSS).Results After treatment,the scores of neurological deficits in patients with acute cerebral infarction in the test group 2 were lower than before treatment,and were lower than those in the test group 1(P<0.05);the total effective rate of treatment in patients with acute cerebral infarction in the test group 2 was excellent in test group 1(P<0.05);after treatment,the laboratory test results of plasma viscosity,whole blood high shear viscosity,and whole blood low shear viscosity of the two groups of patients were lower than before treatment,and the test group 2 was lower in test group 1(P<0.05).Conclusion Ozagrel sodium combined with ginkgo damo injection can further improve the treatment effect of patients with acute cerebral infarction,reduce blood viscosity,and promote the improvement of patients'neurological deficits.