鲜竹沥的化学成分

Chemical Constituents of Retorted Xianzhuli(BAMBUSAE SUCCUS)

目的:研究干馏法鲜竹沥的化学成分。方法:采用大孔吸附树脂、高效液相色谱法对干馏法鲜竹沥进行分离纯化,采用高分辨质谱(HR-ESI-MS)、核磁共振(NMR)等波谱技术鉴定分离单体的结构。结果:从干馏法鲜竹沥中分离到10个化合物,依次鉴定为它乔糖苷(1)、邻二苯酚(2)、2-甲基-对苯酚(3)、4-氧化戊酮酸(4)、(R)-4-羟基-2-氧杂环丁烷酮(5)、1,6-脱水-β-D-吡喃葡萄糖(6)、3-乙酰-1,6-脱水-β-D-吡喃葡萄糖(7)、2-氨基咪唑(8)、5-羟甲基糠醛(9)、2-硝呋喃(10)。结论:化合物2~8、10首次从鲜竹沥中分离得到,其中具有内醚糖结构的化合物6、7与干馏工艺相关。

OBJECTIVE: To explore the ingredients of retorted BAMBUSAE SUCCUS(RBS). METHODS: Macroporous adsorption resins and preparative HPLC were adopted to the separation and purification of RBS. The isolates were subsequently characterized by HR-ESI-MS and NMR. RESULTS: Ten compounds were isolated and identified as tachioside(1), 1, 2-benzenediol(2), 2-methy-1, 4-benzenediol(3), 4-oxopentanoic acid(4), ficumone(5), levoglucosan(6),levoglucosan acetae(7), 2-aminoimidazole(8), 5-hydroxymethylfurfural(9), 2-nitrofuran(10). CONCLUSION: Compounds 2-8 and 10 were isolated from BAMBUSAE SUCCUS for the first time. Among them, compounds 6 and 7, which is characterized by their levoglucosan structure, are assumed to be associated with the retorting process.