睾丸微石症对男性生育能力的影响研究进展

Influence of testicular microlithiasis on male fertility:An update

随着人们对男性健康意识的提高,临床上对睾丸微石症(TM)与男性不育的相关研究日渐增多。TM是一种相对少见的,以睾丸生精小管内多发微小钙化灶(<3 mm)为特征的一种疾病。本文就TM的诊断、流行病学、与男性生育能力相关性及其治疗、随访等方面,将近些年来的研究成果进行总结。目前多数文献发现TM与男性生育能力下降有一定的相关性,但国内外专家观点仍未统一。此外,TM合并男性不育患者的治疗方面仍缺乏有效可靠的药物以及手段,今后仍需要大量的基础及临床研究提供理论依据。

With the increasing awareness of men’s health,more and more clinical studies are reported on the relationship of testicular microlithiasis(TM)with male infertility.TM is a relatively rare disease characterized by multiple microcalcifications(<3 mm)in the seminiferous tubules of the testis.This review summarizes the findings in the studies of the diagnosis,epidemiology,correlation with male fertility,treatment,and follow-up of TM in recent years.Many researches show that TM has a certain correlation with the decline of male fertility,which,however,is not identically agreed on at home and abroad.As for the treatment of TM complicated with male infertility,there is still a lack of effective and reliable drugs and strategies and a need for many basic and clinical studies.