黑色素瘤单病种本体构建研究

Study on the Single-disease Ontology Construction of Melanoma

利用百科知识、临床指南、科技文献、专家经验等多源异构资源进行本体顶层范畴界定,借助Ontofox、Protégé等本体工具采集并组织黑色素瘤疾病、分子异常、症状、解剖结构、药物、干预与操作、并发症等顶层范畴的概念和术语,构建黑色素瘤单病种本体并对其评估,开发本体展示和检索工具,为相关领域研究提供参考。

Multi-source heterogeneous resources such as encyclopaedia,clinical guidelines,scientific literature and expert experience are used to define the top-level category of ontology,and ontology tools such as Ontofox and Protégéare used to collect and organize top-level concepts and terms of melanoma diseases,molecular abnormalities,symptoms,anatomical structures,drugs,interventions and procedures,complications,etc.The single-disease ontology of melanoma is constructed and evaluated,the ontology visualization and retrieval tools are developed,and some useful references are provided for ontology construction research.