术前MRI预测肝细胞癌微血管侵犯的研究进展

Research progress in predicting microvascular invasion of hepatocellular carcinoma by preoperative MRI

微血管侵犯(microvascular invasion,MVI)是影响肝细胞癌术后复发及转移的重要因素之一,与患者预后及治疗密切相关。然而MVI只能通过病理学确诊,通过MRI检查精确预测MVI对选择治疗措施及改善患者预后具有重要意义及发展前景。目前已经提出了较多基于MRI检查的成像特征用于MVI的预测,包括肿瘤大小、数目、包膜不完整、边缘不光滑、动脉期瘤周强化、肝胆期瘤周低信号等。影像组学作为新兴的领域,可能是预测肝细胞癌患者MVI的准确而有效的工具,近年来也被研究者们用于探索与MVI之间的联系。本文就术前MRI检查及基于MRI的影像组学模型预测肝细胞癌MVI的研究进行综述。

Microvascular invasion(MVI)is one of the important factors affecting postoperative recurrence and metastasis of hepatocellular carcinoma,and is closely related to the prognosis and treatment of patients.However,MVI can only be diagnosed by pathology.Accurate prediction of MVI by MRI is of great significance and prospect for selecting treatment measures and improving the prognosis of patients.Many MRI-based imaging features have been proposed for the prediction of MVI,including tumor size,number,incomplete capsule,uneven margins,peritumoral enhancement in arterial phase,and peritumoral hypointensity in hepatobiliary phase.As an emerging field,radiomics may be an accurate and effective tool for predicting MVI in patients with hepatocellular carcinoma,and it has also been used by researchers to explore the link with MVI in recent years.This article reviewed the research on preoperative MRI examination and MRI-based radiomics model for predicting MVI in hepatocellular carcinoma.