温胆汤加味联合耳穴贴压治疗痰热内扰型失眠症临床研究

Clinical Study on Modified Wendan Tang Combined with Auricular Point Pressing with Beans for Insomnia of Internal Harassment of Phlegm-Heat Type

目的:观察温胆汤加味联合耳穴贴压治疗痰热内扰型失眠症的临床疗效。方法:选取86例痰热内扰型睡眠障碍患者,按随机数字表法分为对照组和观察组各43例。对照组给予艾司唑仑口服,观察组给予温胆汤加味联合耳穴压豆治疗。比较2组临床治疗效果,以及治疗前后睡眠质量、睡眠时间变化,并观察治疗过程中的不良反应情况。结果:观察组临床疗效优于对照组,经秩和检验,差异有统计学意义(P<0.05)。治疗前,2组匹兹堡睡眠质量指数量表(PSQI)评分和每晚睡眠时间比较,差异无统计学意义(P>0.05)。治疗后,2组PSQI评分均较治疗前降低(P<0.05),每晚睡眠时间均较治疗前延长(P<0.05);且观察组PSQI评分低于对照组(P<0.05),每晚睡眠时间长于对照组(P<0.05)。观察组不良反应发生率为9.30%,对照组为51.16%,2组比较,差异有统计学意义(P<0.05)。结论:温胆汤加味联合耳穴贴压治疗痰热内扰型失眠症可提高临床疗效,改善睡眠质量,且安全性良好。

Objective:To observe the clinical effect of modified Wendan tang combined with auricular point pressing with beans for insomnia of internal harassment of phlegm-heat type.Methods:A total of 86 cases of patients with sleep disorder of internal harassment of phlegm-heat type were selected and divided into the control group and the observation group according to the random number table method,43 cases in each group.The control group was given the oral administration of esazolam,and the observation group was treated with modified Wendan tang combined with auricular point pressing with beans.The changes of sleep quality and sleep time before and after treatment as well as the clinical effect in the two groups were compared;the adverse reactions during treatment were observed.Results:The clinical efficacy of the observation group was better than that of the control group.By rank sum test,the difference was statistically significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of pittsbugh sleep quality(PSQI) scores and sleep time per night between the two groups(P>0.05).After treatment,PSQI scores in the two groups were decreased when compared with those before treatment(P<0.05),and sleep time per night was increased(P<0.05);the PSQI score in the observation group was lower than that in the control group(P<0.05),and the sleep time was longer(P<0.05).The incidence of adverse reactions was 9.30% in the observation group,lower than that of 51.16% in the control group,the difference being significant(P<0.05).Conclusion:The therapy of modified Wendan tang combined with auricular point pressing with beans for insomnia of internal harassment of phlegm-heat type can improve the clinical effect and sleep quality with good safety.