联合监测血清PCT,BNP,HBP水平变化对脓毒症患者早期诊断和预后评估的临床价值

Clinical Value of Combined Monitoring of Blood PCT,BNP and HBP Levels in the Prognostic Evaluation of Patients with Sepsis

目的探究联合监测血清PCT,BNP,HBP水平变化对脓毒症患者早期诊断和预后评估的临床价值.方法根据治疗结局将100例患者分为治疗有效组(60例)和治疗无效组(40例),对受检者均实施单一监测(PCT,BNP,HBP)、两两联合监测(PCT+BNP、BNP+HBP、HBP+PTC)和PCT+BNP+HBP联合监测,分析比较两组患者的预后情况以及两组患者进行单一监测和联合监测的检出阳性率、敏感性和特异度.结果治疗有效组血清PCT(4.01±1.27)Pg/mL、BNP(61.41±1.27)Pg/mL及HBP水平(29.11±1.16)Pg/mL显著低于治疗无效组(P<0.05);PCT+BNP+HBP联合检测检出阳性率、敏感度和特异性分别达98.00%,96.00%,92.00%,均明显高于单一监测和两项指标联合检测(P<0.05).结论采用PCT+BNP+HBP联合监测,能对脓毒症患者进行有效早期诊断和预后评估.

Objective To explore the clinical value of combined monitoring of blood PCT,BNP and HBP levels in the prognostic evaluation of patients with sepsis.Methods 100 patients with sepsis were selected as the subjects of this study,and the treatment period was from January 2020 to December 2020.All subjects were subjected to joint monitoring of changes in blood PCT,BNP and HBP levels,and the effect of the joint detection was analyzed.In order to clarify the effect.Results After the treatment of the patients,100 patients were divided into 60 patients in the treatment improvement group and 40 patients in the treatment failure group according to the treatment outcome.The blood PCT(4.01±1.27)Pg/mL,BNP(61.41±1.27)of the treatment group was improved.Pg/mL and HBP levels(29.11±1.16)Pg/mL were lower than the treatment-ineffective group(P<0.05).The positive rate,sensitivity and specificity of the combined detection of the three indicators were 98.00%,96.00%,and 92.00%,which were significantly higher than the single monitoring and combined detection of the two indicators,and the difference was statistically significant(P<0.05).Conclusion The combined monitoring of blood PCT,BNP and HBP levels can effectively evaluate the prognosis of patients with sepsis.