金纳米双锥体的制备及对食品污染物的快速检测

Preparation of gold nanobiparamid and its application in rapid detection of food contaminants

制备了一种新颖、可靠、快速的检测平台用于检测食品中多种化学污染物。通过种子两步生长法合成出金纳米双锥体,采用消耗诱导分离法获得纯度接近100%的金纳米双锥体,利用液-液界面自组装法制备出大面积致密的金纳米双锥体表面增强拉曼散射(SERS)活性基底。研究表明,以结晶紫(CV)作为拉曼探针分子,该基底具有较好的SERS灵敏性和重复性;而且对抗生素孔雀石绿(MG)、农药残留福美双(THR)和塑化剂邻苯二甲酸卞酯(BBP)的检测灵敏性较高,检测限分别达到10^(-9)、10^(-9)、10^(-8)mol/L,对酒中BBP的检测限为1.3 mg/kg。

A novel,reliable and rapid detection platform is developed to detect various chemical pollutants in food.Gold nanobiparamid is synthesized by means of a two-step seed growth method,and then gold nanobiparamid with a purity close to 100%is obtained through consumption-induced separation method.Finally,a large-area dense gold nanobiparamid surface-enhanced Raman scattering(SERS)active substrate is prepared through a liquid-liquid interface self-assembly method.The results indicate that the prepared substrate exhibits excellent SERS sensitivity and repeatability when crystalline violet(CV)is used as Raman probe molecule.Moreover,the prepared substrate shows high detection sensitivity to malachite green(antibiotic),thiram(pesticide residues)and butyl benzyl phthalate(plasticizer)in food,with detection limits of 10^(-9)mol·L^(-1),10^(-9)mol·L^(-1)and 10^(-8)mol·L^(-1),respectively.In addition,its detection limit to butyl benzyl phthalate in wine achieves 1.3 mg·kg^(-1).