老年慢性心力衰竭合并肺部感染致病菌分布及耐药性分析

目的探讨老年慢性心力衰竭患者合并肺部感染致病菌分布,并对致病菌及耐药性进行分析.方法选取2019年1月至12月慢性心力衰竭合并肺部感染患者251例,入院后进行痰培养,并对合格痰标本采用法国梅里埃ATB微生物鉴定和药敏分析系统进行致病菌菌株鉴定及其耐药性分析,采用琼脂纸片扩散法(K-B法)进行药物敏感试验.结果251名慢性心力衰竭合并肺部感染患者共培养出183株正常菌群(72.91%),培养出致病菌68株(27.09%),比例最高前3位为:肺炎克雷伯杆菌、铜绿假单胞菌及大肠埃希菌.结论慢性心力衰竭合并肺部感染患者痰培养阳性率较低,革兰阴性菌比例较高,其中铜绿假单胞菌及大肠埃希菌耐药菌株偏多,值得心内科医师关注.

Objective To investigate the distribution of pathogenic bacteria with chronic heart failure complicated with pulmonary infection in elderly patients,and to analyze the drug resistance of pathogenic bacteria.Methods 251 patients with chronic heart failure complicated with pulmonary infection were selected from January 2019 to December 2019,carried out sputum culture after admission.The qualified sputum specimens had been used French merry Emmanuel ATB microbial identification and drug susceptibility analysis system to identify the pathogenic bacteria strains and drug resistance analysis,and had been used the AGAR disc diffusion method(K-B method)for dnig sensitive test.Results A total of 183 strains of normal bacteria(72.91%)and 68 strains of pathogenic bacteria(27.09%)were cultured from 251 patients with chronic heart failure complicated with pulmonary infection.The top 3 strains were Klebsiella pneumoniae,Pseudomonas aeruginosa and Escherichia coli.Conclusion The positive rate of sputum culture in patients with chronic heart failure complicated with pulmonary infection is low,and the proportion of gram-negative bacteria is high,among which Pseudomonas aeruginosa and Escherichia coli are more resistant strains,which should be paid more attention to by cardiologists.