急性脑梗死患者取栓术后症状性颅内出血相关因素分析

目的探讨急性脑梗死患者取栓术后症状性颅内出血(SICH)的危险因素.方法回顾性分析2018年1月至2020年5月连续接受血管内治疗的224例急性缺血性脑梗死患者的临床资料,根据术后有无SICH分为2组,分析相关因素.结果单因素分析显示两组患者既往高血压病史、中性粒细胞数差异有统计学意义(P<0.05),多因素Logistic回归分析结果显示,中性粒细胞升高是急性缺血性脑卒中患者血管内治疗后发生SICH的危险因素(OR=1.192,95%CI1.020~1.393,P<0.05).结论中性粒细胞升高可能是前循环大动脉闭塞致急性缺血性脑卒中患者血管内治疗后SICH风险增加的重要预测因素.

Objective To assess the related factors of symptomatic intracranial hemorrhage after thrombectomy in patients with acute cerebral infarction.Methods A total of 224 patients with acute ischemic cerebral infarction that received continuous endovascular treatment from January 2018 to May 2020 in Hangzhou First People's Hospital affiliated with Zhejiang University were included.The study population was divided into two groups according to the post-operative intracranial hemorrhage condition and the related factors were statistically analyzed.Results Univariate analysis revealed that hypertension and neutrophils history in 2 groups were statistically significant(P<0.05).Multivariate logistic regression analysis showed that high neutrophils count was a risk factor for symptomatic intracranial hemorrhage after endovascular treatment in patients with acute ischemic stroke(OR=1.192,95%CI:1.020~1.393,P<0.05).Conclusion This study demonstrates that high neutrophil count level may be a cmcial predictor for increased SICH risk in patients with acute ischemic stroke due to anterior circulation aorta occlusion after endovascular therapy.