阿托伐他汀联合阿司匹林治疗脑卒中的临床效果及对患者NIHSS评分的影响

Clinical effect of Atorvastatin Combined with aspirin in the treatment of stroke and its influence on NIHSS score

目的探讨阿托伐他汀联合阿司匹林治疗脑卒中的临床效果及对患者国立卫生研究院卒中量表(NIHSS)评分的影响。方法选取2020年1-12月该院收治的脑卒中患者540例,收集其相关临床资料,依据治疗方案的差异分为研究组和对照组,每组270例。对照组常规治疗联合阿司匹林治疗,研究组基础治疗后给予阿托伐他汀联合阿司匹林治疗。对比两组患者临床疗效、神经功能缺损与运动功能评分及血脂水平。结果研究组患者总有效率明显高于对照组,治疗后NIHSS评分均明显低于对照组,运动功能通过运动功能评分量表评分明显高于对照组,差异均有统计学意义(P<0.05)。结论对脑卒中患者施以阿托伐他汀联合阿司匹林治疗能促进临床疗效的提升,还可降低患者NIHSS评分,改善患者日常生活能力,值得应用。

Objective To investigate the clinical effect of atorvastatin combined with aspirin in the treatment of cerebral apoplexy and its influence on NIHSS score.Methods A total of 540 cases of stroke patients admitted to our hospital from January 2020 to December 2020 were selected,and their related clinical data were collected to carry out this study,and they were grouped according to the difference of treatment plan.The control group received conventional treatment and aspirin treatment,and the study group received atorvastatin combined with aspirin treatment after basic treatment.The clinical treatment effect,neurological impairment and motor function scores of the two groups were compared,and the blood lipid levels of the two groups were compared.Results The effective rate of the study group was higher than that of the control group(P<0.05).The NIHSS score of the study group was lower than that of the control group,and the FMA score was higher than that of the control group(P<0.05).The levels of HDL-C in the intervention group were higher than those in the control group,and the levels of TG,LDL-C and TC were lower than those in the control group(P<0.05).Conclusion Atorvastatin combined with aspirin can promote clinical efficacy,reduce NIHSS score,improve the ability of daily living,and regulate the level of blood lipid in stroke patients,which is worthy of application.