生物体内环形挥发性甲基硅氧烷的分布、行为及效应研究进展

Research progress on the distribution,behavior and effects of cyclic volatile methylsiloxanes in organisms

近年来,环形挥发性甲基硅氧烷(cVMSs)因其优异的物化特性而被广泛应用在工业生产和日常生活的各个方面,特别是经常被添加到个人护理品(PCPs)等各类消费品中。目前,人们对cVMSs在环境介质中的污染水平及其迁移转化行为有了一定的了解。另外,cVMSs兼有疏水性和挥发性,且难以进行生物降解,因此该类物质进入环境后潜在的生态风险,特别是其生物富集、生物累积、生物放大和毒性效应等已成为关注的热点。本文综述了cVMSs在全球生物体内的残留水平,并在此基础上总结了cVMSs生物效应等相关研究成果。总体上,众多研究表明cVMSs在某些水生生物体内呈现中等的生物富集性和累积性。然而,与其相对明确的生物富集/累积性相比,目前文献针对cVMSs生物放大效应的研究结果存在明显差异。建议后续的研究能够深入探索其生物效应,尤其是结合其在生物体内的降解过程以及中间产物的毒性数据,进一步评估其生态环境效应和人类健康风险。

Due to their excellent physicochemical properties,cyclic volatile methylsiloxanes(cVMSs)have been widely used in both industrial production and daily life,especially in various consumer products,such as personal care products(PCPs).At present,there have been some researches on distribution,migration and transformation behaviors of cVMSs in environmental matrices.In addition,cVMSs have both hydrophobicity and volatility,and were difficult to be biodegraded.Therefore,the potential ecological risks of cVMSs,especially their bioconcentration,bioaccumulation,biomagnificatioon and toxicity hadbecome a global concern.In this study,the residual levels of cVMS in organisms around the world were reviewed,and then research results on their ecological effects were summarized.In general,cVMSs underwent moderate bioconcentration and bioaccumulation in some aquatic organisms.However,compared with the relatively confirmed bioconcentration/bioaccumulatiion,biomagnification of cVMSs was still a controversial issue.The following research should further explore their biological effects.Especially,combing both their degradation process in organisms and toxic data of intermediate products,the ecological effects and human health risks of these compounds should be further evaluated.