子宫内膜癌病理特征与盆腔淋巴结转移的关系研究

Analysis on relevant factors of lymph node metastasis in endometrial carcinoma

目的探讨子宫内膜癌盆腔和腹腔淋巴结转移的临床特点,为子宫内膜癌的个体化诊治提供依据。方法选取2014年1月至2019年2月本院收治的170例子宫内膜癌患者作为研究对象,回顾性分析其临床及病理资料,对有淋巴转移的高危因素进行统计分析。结果170例子宫内膜癌患者淋巴转移率为11.8%(20/170),主要转移区域为闭孔区域淋巴结。腹主动脉旁淋巴结转移率为3.5%(6/170)。子宫内膜恶性肿瘤组织和病理学类型、癌的分化程度、癌灶大小、有无侵犯宫颈间质、腹腔冲洗液细胞学检查为子宫内膜癌淋巴结转移的高危因素。结论子宫内膜癌最常见的淋巴转移部位为闭孔区域的淋巴结,对于有上述高危因素的子宫内膜癌患者手术方案的制定具有一定指导作用,可为其诊疗个体化提供理论依据。

Objective To explore the clinical features of pelvic and abdominal lymph node metastasis in endometrial cancer,and to provide evidence for individualized diagnosis and treatment of endometrial cancer.Methods 170 endometrial cancer patients in our hospital from January 2014 to February 2019 were selected as study subjects.The clinical and pathological data was retrospectively analyzed,and the risk factors of lymphatic metastasis were statistically analyzed.Results The incidence of lymph node metastasis in 170 endometrial cancer patients was 11.8%(20/170),and the most common site of lymph node metastasis was the obturator area.The incidence of para-aortic lymph node metastasis was 3.5%(6/170).Endometrial cancer histopathology,histological differentiation,tumor size,cervical interstitial involvement,and positive peritoneal cytology were the high risk factors of endometrial cancer lymph node metastasis.Conclusion The most common site of lymph node metastasis in endometrial cancer is the obturator area.For endometrial cancer patients with the above-mentioned high risk factors,it play a certain guiding role in the formulation of surgical plans,which can provide a theoretical basis for individualized diagnosis and treatment.