康妇炎胶囊联合宫腹腔镜再通术治疗输卵管结扎后复通疗效及妊娠结局

Analysis about Pregnancy Outcome and Combined Treatment of Kangfuyan Capsule after Hysterolaparoscopy in Salpingemphraxis Infertility

目的探究康妇炎胶囊联合宫腹腔镜在治疗输卵管结扎复通中的效果,分析联合疗法对妊娠率的影响。方法回顾性分析2014年2月至2019年2月期间121例输卵管结扎术后复通患者的临床资料。根据患者治疗方案分为对照组及治疗组。治疗组在宫腹腔镜输卵管结扎复通术后内服康妇炎胶囊1月。对照组术后不采取任何特殊治疗。对比分析2组患者在术后1 a内的宫内妊娠率、异位妊娠率差异,分析年龄、术后输卵管长度等相关因素与宫内妊娠间相关性。结果治疗组术后1 a内宫内妊娠率为79.6%,远高于对照组56.1%之妊娠率,P<0.05;且治疗组术后异位妊娠率仅3.1%,远低于对照组10.5%之异位妊娠率,P<0.05。对照组宫内妊娠率随时间推移趋于稳定,治疗组宫内妊娠则集中于术后1~4月内。此外,年龄、结扎(吻合)部位、术后输卵管长度与宫内妊娠率高度相关。结论康妇炎胶囊可提高输卵管结扎再通患者宫内妊娠率,降低异位妊娠率。

Objective To explore the effect of Kangfuyan capsule combined with hysteroscopy in the treatment of recanalization of fallopian tube after sterilization,and to analyze the effect of combined therapy on pregnancy rate.Methods A retrospective analysis of the clinical data of 121 patients with tubal ligation recanalization from February 2014 to February 2019.Patients were divided into control group and treatment group.In the treatment group,Kangfuyan capsules were taken orally for 1 month after recanalization.The control group did not take any special treatment after operation.The differences in intrauterine pregnancy rate and ectopic pregnancy rate of the two groups within 1 year were analyzed,and the correlation between age,postoperative fallopian tube length and other related factors were analyzed.Results Within 1 year after surgery,the intrauterine pregnancy rate in the treatment group was 79.6%which was much higher than the 56.1%pregnancy rate in the control group,P<0.05;and the postoperative ectopic pregnancy rate in the treatment group was only 3.1%,which was far lower than the control group(10.5%),P<0.05.The intrauterine pregnancy rate in the control group stabilized over time,while intrauterine pregnancy in the treatment group was concentrated within 1-4 months after surgery.Age,location of sterilization,fallopian tube length after recanalization are highly correlated with intrauterine pregnancy rate.Conclusion Kangfuyan Capsules can increase the rate of intrauterine pregnancy in patients with tubal ligation recanalization,and reduce the rate of ectopic pregnancy。