摘要
肾脏疾病已成为全球范围内危害人类健康的重要公共卫生问题。除高龄、高血压、糖尿病等传统因素外,环境污染也是引发肾脏疾病的重要危险因素,尤其是大气污染及气候因素对肾脏健康的影响不可忽视。大气颗粒物及气态污染物暴露与肾脏疾病的发生、肾功能下降及患者的不良预后密切相关。气候变暖作为全球气候变化的最主要表现,同样会引起急性肾损伤及肾结石等疾病。本文对国内外大气污染及气候因素对肾脏疾病的影响及其生物学机制研究进展进行综述,以期为治理大气污染、应对气候变化,以及制定肾脏疾病人群防治策略提供依据。
Kidney diseases have become an important public health problem worldwide that threatens human health.In addition to traditional risk factors such as advanced age,hypertension,and diabetes,environmental pollution,especially the air pollution and climate change,are also major risk factors for chronic kidney disease.The exposure of airborne particulate matter or gaseous pollutants has been found to be closely associated with the incidence of chronic kidney disease,decline of kidney function,and poor prognosis of patients.As the main manifestation of global climate change,climate warming could also lead to acute kidney injury and nephrolithiasis.This paper reviews the progress in the epidemiological research of the impacts of air pollution and climate change on kidney diseases,in order to provide reference for air pollution control,climate governance,and the development of prevention and control strategies for kidney diseases.
作者
杨超
李鹏飞
张路霞
Yang Chao;Li Peng-Fei;Zhang Lu-Xia(Department of Nephrology,Peking University First Hospital/Peking University Institute of Nephrology,Beijing 100034,China;Research Units of Diagnosis and Treatment of Immune-Mediated Kidney Diseases,Chinese Academy of Medical Sciences,Beijing 100034,China;Advanced Institute of Information Technology,Peking University,Hangzhou 311215,China;National Institute of Health Data Science at Peking University,Beijing 100191,China)
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2022年第1期72-77,共6页
Medical Journal of Chinese People's Liberation Army
基金
国家自然科学基金(82003529,91846101)
北京市科技新星计划交叉学科合作课题(Z191100001119008)
中国医学科学院医学与健康科技创新工程项目(2019-I2M-5-046)
北大百度基金(2019BD017)。
关键词
大气污染
气候变化
慢性肾脏病
急性肾损伤
流行病学
air pollution
climate change
chronic kidney disease
acute kidney injury
epidemiology
