伴有精神症状的自身免疫性脑炎的临床特点分析

Clinical characteristics of autoimmune encephalitis with mental symptoms

目的分析不同抗体类型自身免疫性脑炎患者精神症状的特点。方法回顾性研究了自身免疫性脑炎患者的临床特点。对自免脑患者的精神症状进行分析。对象:2019年9月到2020年12月就诊于中国医科大学附属第一医院神经内科确诊为自身免疫性脑炎的患者。结果抗体阳性为20例,临床表现中最常见的依次是抽搐发作、精神症状、意识障碍、记忆力下降。结论各亚型自身免疫性脑炎患者精神症状无明显差异,即不能通过患者的精神症状判断自免脑抗体类型。

Objective To analyze the characteristics of mental symptoms in patients with autoimmune encephalitis with different antibody types.Methods The clinical characteristics of patients with autoimmune encephalitis were retrospectively studied.The mental symptoms of patients with autoimmune brain were analyzed.Subjects:Patients diagnosed with autoimmune encephalitis admitted to the Department of Neurology,the First Affiliated Hospital of China Medical University from September 2019 to December 2020.Results There were 20 cases with positive antibody,and the most common clinical manifestations were convulsion,mental symptoms,consciousness disorder and memory decline.One tumor was found in NMDAR AE,which was teratoma of ovary.Conclusion The mental symptoms of patients with subtypes of autoimmune encephalitis have no significant difference,that is,the type of autoimmune brain antibodies can not be determined by the patients’major mental symptoms.