类胡萝卜素生物利用率及其乳液递送体系研究进展

Research progress on carotenoid bioavailability and its emulsion delivery system

工作环境与生活状态的改变导致人群亚健康状态以及人口老龄化问题已经引起人们的重视。具有多重生物活性的膳食补充剂对人体健康有多种保护功能,已经成为消费者与研究者共同关注的热点。类胡萝卜素不仅是光合生物中发挥关键活性的天然色素,也常被用作营养补充剂应用于食品工业、制药行业中。然而类胡萝卜素对加工生产条件、环境因素的高敏感性与自身的强疏水性等特性,限制了类胡萝卜素的生物利用率及其在复杂加工食品中的广泛应用;食品基质中存在的其他营养素如脂质、纤维素、蛋白质、矿物元素等也对类胡萝卜素的生物利用率有较大影响。相关研究表明乳液这一特殊的递送体系,能够在保护类胡萝卜素免受环境因素破坏的同时,提高其在人体内的生物利用率。本综述从类胡萝卜素生物利用率多重影响因素的角度出发,分析乳液递送体系对其生物利用率调控的研究进展与应用现状,并展望类胡萝卜素乳液递送体系的未来发展趋势。

With the continuous improvement of material living standard, changes in working environment and living state have led to the development of the sub-health status and the aging of the population. Dietary supplements with multiple biological functions have become a hot topic for consumers and researchers. Carotenoids are not only natural pigments that play a key role in photosynthetic organisms, but also have various protective functions for human health. Therefore, they are often used as nutritional supplements in the food industry and pharmaceutical industry. However, the high sensitivity of carotenoids to processing conditions and environmental factors, as well as their strong hydrophobicity limit the bioavailability of carotenoids and their wide application in complex processed food environments;other nutrients such as lipid, cellulose, protein and mineral elements in food matrix also have great influence on the bioavailability of carotenoids. Related research has shown that emulsion, a special delivery system, can protect carotenoids from environmental factors and improve their bioavailability in the human body.From the perspective of multiple factors affecting the bioavailability of carotenoids, this review focused on the research progress and application status of carotenoids bioavailability regulated by emulsion delivery systems, and looked into the future development trend of these delivery systems.