散瘀消痛散外敷对低位单纯性肛瘘切除术后患者创面愈合、生活质量的影响

Effects of external application of Sanyu Xiaotong powder on postoperative wound healing and quality of life in patients with low simple anal fistula

目的观察散瘀消痛散外敷治疗低位单纯性肛瘘切除术后患者的临床疗效及对创面愈合、生活质量的影响。方法将2019年7月—2020年7月上海中医药大学附属曙光医院肛肠科治疗的70例低位单纯性肛瘘切除术后患者随机分为对照组35例和观察组35例。对照组给予肛肠科常规术后治疗,观察组在此基础上加用散瘀消痛散外敷,2组均治疗2周。比较2组患者临床疗效及创面愈合面积、愈合率、愈合时间,评价2组患者治疗第3,7,14天疼痛评分、创面渗出液评分、肉芽生长评分、生活质量量表(SF-36)评分,并记录不良反应发生情况。结果治疗2周后,观察组总有效率为88.6%(31/35),对照组为68.5%(24/35),观察组明显高于对照组(P<0.05);观察组创面愈合面积、愈合率均明显高于对照组(P均<0.05),创面愈合时间明显短于对照组(P<0.05)。治疗第7天、第14天,2组患者疼痛评分、创面渗出液评分、肉芽生长评分均明显低于治疗第3天(P均<0.05),且观察组均明显低于对照组(P均<0.05);2组患者治疗第3天SF-36评分中心理健康、认知功能、生理功能、社会职能评分比较差异均无统计学意义(P均>0.05),治疗第7天、第14天均明显高于治疗第3天(P均<0.05),且观察组均明显高于对照组(P均<0.05)。观察组和对照组不良反应发生率分别为14.3%(5/35)和31.4%(11/35),观察组明显低于对照组(P均<0.05)。结论散瘀消痛散外敷可有效促进低位单纯性肛瘘切除术后患者创面愈合,减轻症状,提高生活质量,且安全性高。

Objective It is to observe the clinical curative effect of external application of Sanyu Xiaotong powder in the treatment of patients with low simple anal fistula after surgery and its effect on wound healing and quality of life. Methods Seventy patients with low simple anal fistula who were treated in the Department of Anus and Proctology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine were from July 2019 to July 2020 were randomly divided into a control group of 35 cases and an observation group of 35 cases. The control group was given routine postoperative treatment in anorectal department, the observation group was additionally given external application of Sanyu Xiaotong powder, and both groups were treated for 2 weeks. The clinical curative effect, wound healing area, healing rate, and healing time were compared between the two groups, and the pain scores, wound exudate scores, granulation growth scores, and scores of quality of life(SF-36) were evaluated on the 3 rd, 7 th, and 14 th days of treatment in the two groups, and the occurrence of adverse reactions was recorded. Results After 2 weeks of treatment, the total effective rate was 88.6%(31/35) in the observation group and 68.5%(24/35) in the control group, and the observation group was significantly higher than the control group(P<0.05). The wound healing area and healing rate in the observation group were significantly higher than those in the control group(P all<0.05), and the wound healing time was significantly shorter than that in the control group(P<0.05). On the 7 th and 14 th days of treatment, the pain scores, wound exudate scores, and granulation growth scores of the two groups were significantly lower than those on the 3 rd(P all<0.05), and the scores in the observation group were significantly lower than those in the control group(P all<0.05);there was nosignificant difference in the scores of mental health, cognitive function, physiological function, and social function in SF-36 on the 3 rd day between the two groups(P>0.05), but the scores on the 7 th and 14 th days were significantly higher than those on the 3 rd day(P all<0.05), and the scores in the observation group were significantly higher than those in the control group(P all<0.05). The incidence of adverse reactions in the observation group and the control group were 14.3%(5/35) and 31.4%(11/35), respectively, and the observation group was significantly lower than the control group(P<0.05). Conclusion External application of Sanyu Xiaotong powder can effectively promote wound healing, relieve symptoms and improve quality of life with high safety in patients with low simple anal fistula resection after surgery.