老年人握力与认知功能的关联性

The correlation between grip strength and cognitive function in elderly people

目的探讨65岁及以上老年人握力与认知功能之间的关系。方法在武汉市65岁以上老年人中开展现况研究,由经过统一专业培训的调查人员收集握力、认知功能和生活方式等信息,分别采用多重线性回归和Logistic回归分析握力值与认知功能得分和认知障碍之间的关系。结果本次研究对象(70.7±5.1)岁,533例老年人的平均握力为(24.94±9.15)kg。调整社会人口学信息、生活方式因素和疾病史等协变量后,相比于握力Q1组(<18.6 kg),Q2组(18.6~24.1)kg、Q3组(24.2~31.1)kg和Q4组(>31.1 kg)的认知功能得分偏回归系数分别为0.45(-0.36,1.26)、0.40(-0.52,1.32)和1.19(0.07,2.31);认知障碍发生率的OR值分别为0.97(0.43,2.19)、0.79(0.30,2.06)和0.22(0.05,0.92)。当将握力作为连续性变量进行分析时,其每增加1 kg,认知得分增加0.07分,认知障碍的发生风险降低6%。结论提示老年人的握力水平与认知功能表现呈正相关,握力较低与认知障碍风险增加相关,应当积极关注社区老年人群握力情况。

Objective To explore the association between grip strength and cognitive function inelderly people aged 65 years and over.Methods Information on grip strength.cognitive function,and lifestyle in the elderly population aged 65 years and over in Wuhan was collected by unifiedprofessionally trained investigators.A total of 533 study subjects aged(70.7±5.1)years were groupedby quartile into four grip strength groups of Q1(<18.6 kg),Q2(18.6~24.1 kg),Q3(24.2~31.1kg),Q4(>31.1 kg).Multiple linear regression and Logistic regression analyses were used to analyzethe relationship of grip strength with cognitive function scores and cognitive impairment.ResultsThe mean grip strength of the 533 subjects was(24.94±9.15)kg.After adjusting forsociodemographic characteristics,lifestyle factors,history of diseases as compared with grip strengthQ1 group,the linear regression coefficients(Beta value)of cognitive scores and 95%confidenceintervals(95%CI)showed statistically significantly positive correlation[0.45(-0.36,1.25),0.40(-0.52,1.32)and 1.19(0.07,2.31),all P≤0.05]only between cognitive scores and grip strength Q2、Q3 and Q4 valuc;and the odds ratio and 95%Cl of incidence of cognitive impairment were 0.97(0.43,2.21)for grip strength Q2,0.79(0.30,2.06)for grip strength Q3,and 0.22(0.05,0.92)for gripstrength Q4.Considering grip strength as the continuous variable,the risk of cognitive impairment wasdecreased by 6%and the cognitive score was increased by 0.07 with per 1kg increase of grip strength.Conclusions The results of this study suggest that there is a positive correlation between gripstrength and cognitive function in the elderly population,and a lower grip strength is related to increased risk of cognitive impairment.More attention should be paid to the grip strength of the elderly in the community.