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壳聚糖及其在药物制剂和生物技术中的应用 被引量:2

Chitosan and its application in pharmaceutical preparations and biotechnology
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摘要 壳聚糖是一种无毒、天然的化合物,属于甲壳质的衍生物,在溶液中可以和蛋白多糖、粘多糖等发生产生反应。壳聚糖的特性也比较独特,具有抗菌性、吸附性、生物相容性等多种特性,因此在医学领域的应用价值非常高。近年来,以壳聚糖作为载体的药物,在稳定性、药效等方面具有良好表现。未来随着研究的深入,其应用范围也会更为广泛,也会成为药物制剂中的重要敷料。本文详细分析了壳聚糖的应用情况,主要从医用材料和药物制剂,以及生物技术方面的应用展开综述。 Chitosan is a non-toxic,natural compound,a derivative of chitin,which can react with proteoglycans and mucopolysaccharides in solution.Chitosan has unique characteristics,such as antibacterial,adsorption,and biocompatibility.Therefore,its application value in the medical field is very high.In recent years,drugs using chitosan as a carrier have shown good performance in terms of stability and efficacy.In the future,with the deepening of research,its application range will be wider,and it will also become an important dressing in pharmaceutical preparations.In this paper,the application of Chitosan was analyzed in detail,mainly from medical materials and pharmaceutical preparations,as well as biotechnology applications.
作者 林蒙 LIN Meng(Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China)
出处 《医药前沿》 2022年第3期17-19,共3页 Journal of Frontiers of Medicine
关键词 壳聚糖 药物制剂 抗菌性 载体 Chitosan Pharmaceutical preparations Antibacterial Carrier
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