高压氧综合治疗创伤性脑外伤综合征20例疗效观察

Observation of the curative effect of combined hyperbaric oxygen therapy on 20 cases of traumatic brain injury syndrome

目的探讨高压氧综合治疗创伤性脑外伤综合征的临床疗效。方法选取2019年1月至2020年12月在西北大学附属神木医院住院治疗的脑外伤后综合征患者40例作为研究对象,按照数字表法随机分为常规组和高压氧组,每组20例。常规组给予内科对症治疗,高压氧组除接受对症治疗外同时给予高压氧治疗。2组患者分别在治疗前、治疗1个月和治疗2个月采用Rivermead脑震荡后综合征评估量表(RPQ)评价其主观症状严重程度,采用社会活动功能量表(FAQ)进行生活自理能力评价。结果2组患者治疗1个月后RPQ评分和FAQ评分均较治疗前明显降低(P<0.05),且高压氧组治疗后RPQ评分显著低于同期常规组(P<0.05)。治疗2个月后,常规组RPQ评分和FAQ评分与治疗1个月比较差异无统计学意义(P>0.05),而高压氧组RPQ评分和FAQ评分与本组治疗1个月和常规组治疗2个月比较差异均有统计学意义(P<0.05)。与治疗前比较,2组患者治疗1个月记忆力、执行能力、注意力和信息处理能力均显著升高(P<0.05),且高压氧组治疗后记忆力和注意力评分显著高于同时期常规组(P<0.05),而执行能力和信息处理能力比较差异无统计学意义(P>0.05)。治疗2个月后,常规组各项评分与本组治疗1个月比较差异无统计学意义(P>0.05),而高压氧组记忆力和注意力评分较本组治疗1个月和常规组治疗2个月差异均有统计学意义(P<0.05)。结论高压氧综合治疗脑外伤后综合征能够有效改善患者主观症状和生活质量,提高认知能力。

Objective To investigate the curative effect of combined hyperbaric oxygen therapy in the treatment of traumatic brain injury(TBI)syndrome.Methods A total of 40 patients with post-TBI syndrome admitted in Shenmu Hospital affiliated to Northwest University from January 2019 to December 2020 were selected as the research subjects.According to the random number table method,they were divided into conventional group and hyperbaric oxygen group,with 20 cases in each group.The conventional group was given symptomatic drugs,and the hyperbaric oxygen group was additionally treated with hyperbaric oxygen on the basis of symptomatic drugs.Before treatment,one month after treatment,and two months after treatment,the subjective symptom severity was evaluated by the Rivermead Post-concussion Symptoms Questionnaire(RPQ),and the ability of self-care was evaluated by the Functional Activities Questionnaire(FAQ).Results After one month of treatment,the RPQ and FAQ scores of the two groups after treatment were significantly lower than those before treatment(P<0.05),and the RPQ score of the hyperbaric oxygen group was significantly lower than that of the conventional group during the same treatment period(P<0.05).After two months of treatment,there was no statistically significant difference in the RPQ and FAQ scores of the conventional group compared with those of the same group after one month of treatment(P>0.05),while there were statistically significant differences in the RPQ and FAQ scores of the hyperbaric group compared with those of the same group after one month of treatment and those of the conventional group after two months of treatment(P<0.05).Compared with those before treatment,the memory,executive ability,attention,and information processing ability of the two groups were significantly improved after one month of treatment(P<0.05),and the scores of memory and attention in the hyperbaric oxygen group were significantly higher than those of the conventional group during the same treatment period(P<0.05),but there was no significant difference in the executive ability and information processing ability(P>0.05).After two months of treatment,there was no statistically significant difference in the scores of the conventional group compared with those of the same group after one month of treatment(P>0.05),while there were statistically significant differences in the memory and attention scores of the hyperbaric group compared with those of the same group after one month of treatment and those of the conventional group after two months of treatment(P<0.05).Conclusion Combined hyperbaric oxygen therapy can effectively improve the subjective symptoms,life quality,and cognitive ability of patients with post-TBI syndrome.