溶血危象并输血困难1例

A case of hemolytic crisis with difficult in blood transfusion

溶血危象患者多表现为在数小时至数天内发生的血红蛋白明显下降,疾病的发生、发展非常急骤,严重者可发生弥散性血管内凝血(DIC)合并多器官损伤,对患者生命造成威胁。本文报道1例发生溶血危象并输血困难的患者,通过稀释法鉴定不规则抗体筛查,选择ABO和Rh分型一致的去白细胞悬浮红细胞联合血浆置换治疗的病例。1 资料与方法1.1 资料患者,女,36岁,入院前3 d无明显诱因出现头痛,无喷嚏流涕、咳嗽咳痰、腹痛腹泻、尿频尿痛及腰痛等。

In patients with hemolytic crisis, the hemoglobin is often significantly reduced within a few hours to a few days, and the development of the disease is very rapid.In severe cases, disseminated intravascular coagulation(DIC) combined with multiple organ damage may threaten the lives of patients.This article reports a case of a patient with hemolytic crisis and difficulty in blood transfusion.The dilution method was used to identify irregular antibody screening and selected leukocyte-removed suspended red blood cells with consistent ABO and Rh group combined with plasma exchange therapy.