256排探测器CT自由呼吸冠状动脉钙化积分扫描可行性研究

Feasibility Study of Free-Breathing Coronary Artery Calcium Score Scanning using 256-Detector Computed Tomography

目的评价利用256排探测器CT行自由呼吸冠状动脉钙化积分扫描的可行性。方法 100例钙化积分扫描受检者随机分为两组:A组(50例)屏气扫描,B组(50例)自由呼吸扫描。比较两组受检者心率、主动脉平均CT值、CT值标准差、有效剂量、斑块运动伪影主观评分。比较两组钙化积分,包括Agatston积分、体积积分(mm;)、质量积分(mg)及基于Agatston积分的心血管事件危险分层。结果两组受检者一般资料、主动脉平均CT值、CT值标准差、有效剂量的差异无统计学意义(P>0.05)。两组间Agatston积分(A组188.10±445.84;B组152.26±321.86)、质量积分(A组24.64±54.40 mg;B组22.60±51.19 mg)、体积积分(A组73.72±159.49 mm;B组63.58±120.40 mm;)及危险分层差异无统计学意义(P>0.05)。结论利用256排探测器CT行自由呼吸冠状动脉钙化积分扫描,积分计算结果、辐射剂量等与屏气扫描无差别。

Objective To evaluate the feasibility of free-breathing coronary artery calcium score(CACS) scanning using 256-detector computed tomography. Methods 100 patients who underwent CACS scanning were randomly assigned to two groups.50 examinations were performed during breath-holding(group A),and the remaining 50 were performed during free-breathing(group B).Heart rates, CT attenuation values and their standard deviations in the ascending aorta, subjective motion artifact scores and effective doses were compared between the two groups.Agatston scores, mass scores, volume scores and risk classifications based on Agatston score were also compared. Results No significant differences were observed in heart rates, CT values and their standard deviations and effective doses between the breath-holding and free-breathing groups(P>0.05).The differences in Agatston scores(188.10±445.84 vs.152.26±321.86),mass scores(24.64±54.40 mg vs.22.60±51.19 mg),volume scores(73.72±159.49 mm;vs.63.58±120.40 mm;) and risk classifications, were not significant between the two groups(P>0.05). Conclusion CACS scanning during free-breathing using 256-detector CT showed no significant difference in calcium scores and risk classifications based on Agatston score compared with that during breath-holding.