应用彩色多普勒超声测量胎儿肾动脉血流指数预测胎儿生长受限

Using color Doppler ultrasound to measure fetal renal artery blood flow index to predict fetal growth restriction

目的探索彩色多普勒超声对生长受限胎儿肾脏的血流评价价值。方法筛选500例孕妇,经超声及分娩结果分为FGR(胎儿生长受限,fetal growth restriction,FGR)组及非FGR组,获取孕妇及新生儿的一般信息。两组均进行彩色多普勒超声测量胎儿的肾动脉搏动指数(renal artery pulsatility index,RAPI)、肾动脉阻力指数(renal artery resistance index,RARI)、S/D值等数值。比较两组孕妇一般信息及肾血流量值。结果FGR孕妇体重及身体质量指数(body mass index,BMI)均低于非FGR孕妇。FGR组新生儿出生体质量、足月儿比例均低于非FGR组,两组顺产率并无统计学差异。两组胎儿肾动脉血流指数发现,FGR组胎儿RAPI、RARI、S/D值均高于对照组,两组差异具有统计学意义。结论使用彩色多普勒超声对胎儿的肾动脉RAPI、RARI、S/D值进行评估可能成为FGR产前诊断的新工具。

Objective To explore the value of color Doppler ultrasound in evaluating the blood flow of the kidneys of growth-restricted fetuses.Methods 500 pregnant women were screened and divided into FGR group and non-FGR group by ultrasound and delivery results to obtain general information of pregnant women and newborns.Both groups performed color Doppler ultrasound to measure the fetal renal artery RAPI,RARI,S/D value and other values.The general information and renal blood flow values of the two groups of pregnant women were compared.Results The weight and BMI index of FGR pregnant women were lower than those of non-FGR pregnant women.The birth weight and the proportion of full-term infants in the FGR group were lower than those in the non-FGR group,and there was no statistical difference in the rate of normal delivery between the two groups.The fetal renal artery blood flow index of the two groups found that the fetal RAPI,RARI,and S/D values of the FGR group were higher than those of the control group,and the difference between the two groups was statistically significant.Conclusion Using color Doppler ultrasound to evaluate the fetal renal artery RAPI,RARI,S/D value may become a new tool for prenatal diagnosis of FGR.