硫酸镁联合抗母体休克治疗胎盘早剥的临床效果

Clinical effect of magnesium sulfate combined with anti-maternal shock in the treatment of placental abruption

目的观察硫酸镁联合抗母体休克治疗胎盘早剥的临床效果。方法选取2017年1月-2018年12月海南省屯昌县人民医院妇产科收治的胎盘早剥孕妇128例,按照随机单双数法分为观察组和对照组各64例。对照组给予抗母体休克治疗,观察组在对照组的基础上联合硫酸镁治疗。比较2组产妇分娩孕周、产程时间、妊娠结局及新生儿结局。结果观察组孕妇分娩孕周长于对照组(P<0.01),2组产程时间比较差异无统计学意义(P>0.05)。观察组孕妇剖宫产率为15.62%,低于对照组的40.62%(P<0.01);观察组阴道分娩率为84.38%,高于对照组的54.69%(P<0.01);2组子宫切除率、产后出血率比较差异无统计学意义(P> 0.05)。观察组健康新生儿占比为71.87%,高于对照组的40.62%(P<0.01);非健康新生儿占比为23.44%,低于对照组的59.38%(P<0.01);2组新生儿病死率比较差异无统计学意义(P> 0.05)。结论硫酸镁联合抗母体休克治疗对胎盘早剥孕妇进行干预可有效提升治疗效果,可有效改善妊娠结局,具有临床应用价值。

Objective To observe the clinical effect of magnesium sulfate combined with anti-maternal shock in the treatment of placental abruption.Methods From January 2017 to December 2018, 128 cases of placental abruption pregnant women admitted to the Department of Obstetrics and Gynecology of Tunchang County People′s Hospital in Hainan Province were selected, and they were divided into observation group and control group with 64 cases each according to the random odd and even number method. The control group was given anti-maternal shock treatment, and the observation group was treated with magnesium sulfate on the basis of the control group. The gestational week, labor time, pregnancy outcome and neonatal outcome of the two groups were compared.Results The pregnant women in the observation group had a longer delivery gestational circumference than the control group(P< 0. 01), and there was no significant difference in the time of labor between the two groups(P> 0. 05). The cesarean section rate of pregnant women in the observation group was 15. 62%, which was lower than 40. 62% of the control group(P<0. 01). The vaginal delivery rate of the observation group was 84. 38%, which was higher than 54. 69% of the control group(P<0. 01). There were no significant difference in hysterectomy rate and postpartum hemorrhage rate between the two groups(P> 0. 05). The proportion of healthy newborns in the observation group was 71. 87%, which was higher than 40. 62% in the control group(P<0. 01). The proportion of unhealthy newborns was 23. 44%,which was lower than 59. 38% in the control group(P<0. 01). There was no significant difference in the mortality of newborns between the two groups(P>0. 05).Conclusion Magnesium sulfate combined with anti-maternal shock can effectively improve the therapeutic effect of pregnant women with placental abruption, and can effectively improve the pregnancy outcome, which has clinical application value.