摘要
We present GranatumX,a next-generation software environment for single-cell RNA sequencing(scRNA-seq)data analysis.GranatumX is inspired by the interactive webtool Granatum.GranatumX enables biologists to access the latest scRNA-seq bioinformatics methods in a web-based graphical environment.It also offers software developers the opportunity to rapidly promote their own tools with others in customizable pipelines.The architecture of GranatumX allows for easy inclusion of plugin modules,named Gboxes,which wrap around bioinformatics tools written in various programming languages and on various platforms.GranatumX can be run on the cloud or private servers and generate reproducible results.It is a community-engaging,flexible,and evolving software ecosystem for scRNA-seq analysis,connecting developers with bench scientists.GranatumX is freely accessible at http://garmiregroup.org/granatumx/app.
基金
This research was supported by grants from the National Institute of Environmental Health Sciences(NIEHS)through funds provided by the trans-NIH Big Data to Knowledge(BD2K)initiative(www.bd2k.nih.gov
Grant No.K01ES025434)
the National Institutes of Health/National Institute of General Medical Sciences(NIH/NIGMS
Grant No.P20 COBRE GM103457)
the National Library of Medicine(NLM
Grant No.R01 LM012373)
the National Institute of Child Health and Human Development(NICHD,Grant No.R01 HD084633)awarded to LXG.
