摘要
全球科学家在新冠病毒疫情的巨大挑战中从未停止生命科学研究的步伐,2021年生命科学及相关学科仍然取得了长足的进展。概述了2021年生命科学领域最具代表性的若干项前沿研究,对蛋白质结构预测、膜蛋白结构解析、转录起始复合物的解析、人工合成淀粉、新冠病毒中和抗体、基因编辑与疾病治疗、体外胚胎培养、迷幻药与精神疾病治疗、新型干涉单分子定位显微镜和第二代微型化双光子显微镜的研发等研究及技术领域的突破进行梳理和回顾。
Human activities in the broad area of sci-tech research have continued despite the still rampant global COVID-19 pandemic.In the past 2021,significant progress was made in bioscience and many related disciplines.This review highlights a few breakthroughs that directly addressed both immediate and long term needs of humans in facing those contingent and constant challenges.Specifically,we briefly present to the reader the progress made in the fields of theoretical and practical structure biology,chemical biology,COVID-19 antibody development,application of gene editing techniques,drug treatment for human mental disorders and development in imaging techniques.2021 will be remembered for those Chinese scientists who made their particular contributions to the frontier research.
作者
蒋嘉彦
朱芳
李聪
王呈呈
胡荣贵
JIANG Jiayan;ZHU Fang;LI Cong;WANG Chengcheng;HU Ronggui(Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China;Center for Excellence in Molecular Cell Science,University of Chinese Academy of Sciences,Shanghai 200032,China;Medical School,Guizhou University,Guiyang 550025,China)
出处
《科技导报》
CAS
CSCD
北大核心
2022年第1期96-112,共17页
Science & Technology Review
基金
科技部国家重点研发计划项目(2021ZD0203900,2019YFA0802103)
国家自然科学基金委化学科学部项目(81525019)
浙江省重点研发计划项目(2020C03G2012037)
国家自然科学基金项目(31960179)