早产儿宫内感染的危险因素及临床特征分析

Analysis on Risk Factors and Clinical Characteristics of Intrauterine Infection in Premature Infants

目的:分析早产儿宫内感染的危险因素及临床特征。方法:2019年10月-2020年10月收治早产儿120例,根据是否发生宫内感染分为两组,各60例。对照组未发生宫内感染;观察组发生宫内感染。比较两组早产儿与母亲的基本资料,采用Logistic对观察组诱发宫内感染的因素进行分析;并比较两组早产儿并发症发生率。结果:经Logistic多因素分析,发现观察组中诱发宫内感染的独立危险因素有早产儿母亲未规范产检、阴道检查次数>4次、母亲接受过侵入性操作、母亲存在阴道炎与盆腔炎、母亲羊水过少、胎膜早破时间≥12 h。观察组并发症发生率明显高于对照组,差异有统计学意义(P<0.05)。结论:诱发早产儿宫内感染的危险因素较多,且宫内感染早产儿发生并发症的风险明显高于未感染者。因此临床需提高警惕,加强宫内感染的早期防治措施,保证早产儿的安全。

Objective:To analyze the risk factors and clinical features of intrauterine infection in premature infants.Methods:From October 2019 to October 2020,120 cases of premature infants were admitted and divided into two groups according to whether there were intrauterine infections,with 60 cases in each group.No intrauterine infection occurred in the control group;intrauterine infection occurred in the observation group.The basic data of premature infants and their mothers in the two groups were compared,and the factors that induced intrauterine infection in the observation group were analyzed by Logistic analysis;and the incidence of complications in the two groups of premature infants was compared.Results:After Logistic multivariate analysis,it was found that the independent risk factors for intrauterine infection in the observation group were the premature mother's non-standardized birth check,the number of vaginal examinations>4 times,the mother had received invasive procedures,the mother had vaginitis and pelvic inflammatory disease,the mother's oligohydramnios and premature rupture of membranes lasted≥12 hours.The incidence of complications in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:There are many risk factors that induce intrauterine infection in premature infants,and the risk of complications in premature infants with intrauterine infection is significantly higher than that in uninfected infants.Therefore,clinical vigilance needs to be strengthened to strengthen the early prevention and treatment measures of intrauterine infection,and ensure the safety of premature infants.