可见光催化构建碳氮键的研究进展

Recent Advances in Visible-light Catalyzed Formation of Carbon-nitrogen Bonds

可见光是一种清洁的可再生能源,利用可见光代替传统的热能进行化学转化具有绿色、高效的优点。碳氮键是广泛存在于多种生物活性分子和药物分子中的重要化学键,光催化构筑碳氮键在有机和药物化学领域中具有重要研究意义。近年来光催化形成碳氮键研究得到了快速发展,许多新颖的合成方法不断涌现。综述了可见光催化构建C(sp^(2))—N键和C(sp^(3))—N键的研究新进展,并对部分反应机理进行了评述。

Visible light is an efficient,clean,and renewable energy.Instead of traditional thermal conditions,visible light catalyzed chemical transformations have huge advantages such as green and high efficiency.Carbon-nitrogen bonds are important chemical bonds in bioactive and medicinal molecules.Construction of carbon-nitrogen bonds is of significance in organic and pharmaceutical chemistry.Recently,various novel visible-light catalyzed synthetic carbon-nitrogen bond formation methods have been developed rapidly.This review will be focused on the recent research issues on visible light catalyzed C(sp^(2))—N and C(sp^(3))—N bond formation,and further review about some possible reaction mechanisms is also made.