磁共振动态对比增强联合扩散加权成像在前列腺癌患者诊断中的应用价值

Application Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Combined with Diffusion-Weighted Imaging in Diagnosis of Prostate Cancer Patients

目的:探讨磁共振动态对比增强(DCE-MRI)联合扩散加权成像(DWI)在前列腺癌(PCA)患者诊断中的应用价值。方法:2018年10月-2020年10月收治PCA患者60例(PCA组)及良性前列腺增生(BPH)患者60例(BPH组),所有患者均进行常规磁共振成像(MRI)、DCE-MRI及DWI检查。回顾性分析患者临床资料、检查方法及结果。结果:PCA组患者以高信号为主,部分患者表现为稍高信号;BPH组以稍高信号为主,部分患者表现为低、等、混杂信号。PCA组Kep、Ktrans值高于BPH组,表观弥散系数(ADC)值低于BPH组,差异有统计学意义(P<0.05)。DCE-MRI联合DWI对PCA的灵敏度高于DCE-MRI,差异有统计学意义(P<0.05)。DCE-MRI联合DWI的准确度高于DCE-MRI、DWI,差异有统计学意义(P<0.05)。结论:DCE-MRI及DWI对PCA均具有较高的诊断价值,联合使用DCE-MRI及DWI诊断PCA,可以明显提高诊断准确率。

Objective: To explore the application value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with diffusion-weighted imaging(DWI) in the diagnosis of prostate cancer(PCA) patients. Methods: From October 2018 to October 2020, 60 patients with PCA(PCA group) and 60 patients with benign prostatic hyperplasia(BPH)(BPH group) were selected. All patients underwent routine MRI, DCE-MRI and DWI examinations. The clinical data, examination methods and results were analyzed retrospectively. Results: The PCA group was mainly high signal, and some patients showed slightly high signal. The BPH group was mainly slightly high signal, and some patients showed low, equal, and mixed signals. The values of Kep and Ktrans in the PCA group were higher than those in the BPH group, and the apparent dispersion coefficient(ADC) values were lower than those in the BPH group, the differences were statistically significant(P<0.05). The sensitivity of DCE-MRI combined with DWI to PCA was higher than DCE-MRI, the difference was statistically significant(P<0.05). The accuracy of DCE-MRI combined with DWI was higher than DCE-MRI and DWI, the difference was statistically significant(P<0.05). Conclusion: Both DCE-MRI and DWI have high application value for PCA. The combined use of DCE-MRI and DWI to diagnose PCA can significantly improve the diagnostic efficiency of PCA.