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混合磨玻璃结节肺腺癌的CT表现与其病理相关性分析 被引量:2

Correlation Between CT Findings and Pathology of Lung Adenocarcinoma with Mixed Ground Glass Nodules
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摘要 目的:分析混合磨玻璃结节肺腺癌的CT表现与其病理相关性。方法:择取2019年1月~2021年1月来本院就诊确定为肺部混合磨玻璃结节(mGGN)患者120例为研究对象。开展CT检查以及病理学检查,分析混合磨玻璃结节肺腺癌的CT表现与其病理相关性。结果:IAC组74例、MIA组30例、AIS组16例。三组患者基线资料无明显差别(P>0.05),可比。三组间结节实性成分边界、规格、CT值、比例存在统计学意义(P<0.05)。实性成分位置以及分布无统计学意义,P>0.05。结节的形态、规格、血管集束征、空气支气管征、胸膜凹陷征存在统计学意义,P<0.05;结节空泡征、毛刺征、分叶征以及位置无统计学意义,P>0.05。结节规格预测结节腺癌最佳截值是15.6mm,敏感性0.793,特异性0.784。AUC为0.821,95%CI为0.739~0.902。实性成分规格预测腺癌最佳截值5.6mm,敏感性0.765,特异性0.812。AUC为0.890,95%CI为0.835~0.946。实性成分比例预测腺癌最佳截值38.8%,敏感性0.737,特异性0.936。AUC为0.875,95%CI为0.813~0.938。实性成分CT值预测腺癌最佳截值为-150.0 HU,敏感性0.695,特异性0.827。AUC为0.814,95%CI为0.737~0.891。结论:混合磨玻璃结节肺腺癌的CT表现和疾病本身的病理改变存在一定关联性,病灶结节规格、实性成分规格、实性成分CT值对于疾病的病理等级分级有着一定预测价值。 Objective:To analyze the correlation between CT findings and pathology of lung adenocarcinoma with mixed ground glass nodules.Methods:120 patients with pulmonary mggn(mixed ground glass nodules)were selected from January 2019 to January 2021.CT and pathological examination were carried out to analyze the correlation between CT findings and pathology of lung adenocarcinoma with mixed ground glass nodules.Results:There were 74 cases in IAC group,30 cases in MIA group and 16 cases in AIS group.There was no significant difference in baseline data among the three groups(P>0.05).The boundary,specification,CT value and proportion of solid components of nodules among the three groups were statistically significant(P<0.05).The location and distribution of solid components were not statistically significant(P>0.05);The best cut-off value of nodule size was 15.6mm,sensitivity was 0.793,specificity was 0.784.AUC was 0.821,95%CI was 0.739-0.902.The best cut-off value,sensitivity and specificity of solid components for predicting adenocarcinoma were 5.6mm,0.765 and 0.812,respectively.AUC was 0.890,95%CI was 0.835-0.946.The best cut-off value,sensitivity and specificity were 38.8%,0.737 and 0.936 respectively.AUC was 0.875,95%CI was 0.813-0.938.The best cut-off value of solid component CT value for predicting adenocarcinoma was-150.0 Hu,the sensitivity was 0.695,and the specificity was 0.827.AUC was 0.814,95%CI was 0.737-0.891.Conclusion:The CT findings of mixed ground glass nodule lung adenocarcinoma have certain correlation with the pathological changes of the disease itself.The size of the lesion nodule,the size of solid components and the CT value of solid components have certain predictive value for the pathological grade of the disease.
作者 甘荣坤 李亮 林怀雄 陈思敏 刘昌华 GAN Rong-kun;LI Liang;LIN Huai-xiong;CHEN Si-min;LIU Chang-hua(Medical Imaging Department,Chenggong Hospital Affiliated to Xiamen University,Fujian Xiamen 361000)
出处 《中国医疗器械信息》 2022年第3期64-67,共4页 China Medical Device Information
关键词 混合磨玻璃结节 肺腺癌 CT表现 病理结果 相关性 mixed ground glass nodules lung adenocarcinoma CT findings pathological results were analyzed relevance
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