持续低效缓慢血液透析与普通血液透析在终末期糖尿病肾病患者中的对照研究

A Comparative Study of Continuous Low-Efficiency Slow Hemodialysis and General Hemodialysis in Patients with End-Stage Diabetic Nephropathy

目的:比较终末期糖尿病肾病持续低效缓慢血液透析与普通血液透析的效果。方法:2017年1月~2020年2月选取160例终末期糖尿病肾病患者展开探究分析,选择随机数字表法分为两组,即对照组(n=80)和观察组(n=80),对照组行普通血液透析,观察组持续低效缓慢血液透析。结果:PO_(4)、BUN、β2-MG以及ALB等指标血清溶质下降率观察组均小于对照组(P<0.05)。高血压、内瘘闭塞、心血管病变等并发症发生率与对照组比较,观察组并发症发生率显著较低(P<0.05);经治疗后各项炎症指标均降低,两组之间比较观察组较对照组低(P<0.05)。治疗后FINS、FBG、Homa-IR水平两组患者均降低,且观察组低于对照组(P<0.05)。结论:终末期糖尿病肾病应用持续低效缓慢血液透析治疗的效果优于普通血液透析,改善了血清溶质下降率。

Objective:To compare the effect of continuous low efficiency and slow hemodialysis and ordinary hemodialysis in end-stage diabetic nephropathy.Methods:From January 2017 to February 2020,160 patients with end-stage diabetic nephropathy were selected for exploration and analysis,and were divided into two groups by random number table method,namely the control group(n=80)and the observation group(n=80),the control group was treated with ordinary hemodialysis,and the observation group was treated with continuous low-efficiency slow hemodialysis.Results:The decrease rate of serum solutes in PO_(4),BUN,β2-MG and ALB in the observation group was lower than that in the control group(P<0.05).Compared with the control group,the incidence of complications such as hypertension,internal fistula occlusion,and cardiovascular disease was significantly lower in the observation group(P<0.05).The group was lower than the control group(P<0.05).After treatment,the levels of FINS,FBG and Homa-IR in both groups were decreased,and the observation group was lower than the control group(P<0.05).Conclusion:End-stage diabetic nephropathy using continuous low-efficiency and slow hemodialysis is better than ordinary hemodialysis and improves the rate of serum solute decline.