彩色多普勒超声检测甲状腺结节内钙化对鉴别甲状腺癌和甲状腺良性病变的临床价值

The Clinical Value of Color Doppler Ultrasound in the Detection of Calcification in Thyroid Nodules in the Differentiation of Thyroid Cancer from Benign Thyroid Lesions

目的:探讨彩色多普勒超声检查甲状腺结节内钙化以鉴别甲状腺良性病变与甲状腺癌的临床价值。方法:将2019年2月~2021年2月于本院接受治疗的甲状腺结节152例患者纳入本次研究,回顾性分析所有患者的术后病理结果与彩色多普勒超声相关资料,探讨鉴别良恶性病变时彩超检测甲状腺结节内钙化的价值,记录下最终的结果。结果:术后病理结果证实152例甲状腺结节中甲状腺良性疾病共105例(69.1%),47例(30.9%)恶性甲状腺结节,其中甲状腺乳头状癌40例(85.1%),滤泡状癌3例(6.4%),髓样癌4例(8.5%)。恶性甲状腺结节中,微钙化率为33例(70.2%),无钙化率为8例(17.0%),与良性甲状腺结节的微钙化率为3例(2.9%)、无钙化率为94例(89.5%)比较差异均有统计学意义(P<0.05)。恶性甲状腺结节中,边缘性钙化率为3例(6.4%),粗钙化率为3例(6.4%),与良性甲状腺结节的边缘性钙化率为3例(2.9%),粗钙化率为5例(4.8%)相比差异不明显(P>0.05)。结论:彩色多普勒超声检测甲状腺结节内钙化对鉴别甲状腺癌和甲状腺良性病变的临床价值较高,能够提高疾病的检出率。

Objective:To investigate the clinical value of color Doppler ultrasonography in the detection of calcification in thyroid nodules to distinguish benign thyroid lesions from thyroid cancer.Methods:A total of 152 patients with thyroid nodules who received treatment in our hospital from February 2019 to February 2021 were included in this study.Postoperative pathological results and color Doppler ultrasound related data of all patients were retrospectively analyzed to explore the value of color Doppler ultrasound detection of calcification in thyroid nodules when differentiating benign and malignant lesions,and the final results were recorded.Results:Among 152 cases of thyroid nodules,105 cases(69.1%)were benign,47 cases(30.9%)were malignant,including 40 cases(85.1%)of papillary thyroid carcinoma,3 cases(6.4%)of follicular thyroid carcinoma and 4 cases(8.5%)of medullary thyroid carcinoma.In malignant thyroid nodules,the microcalcification rate was 33 cases(70.2%)and the non-calcification rate was 8 cases(17.0%),which were significantly different from that in benign thyroid nodules 3 cases(2.9%)and 94 cases(89.5%)(P<0.05).In malignant thyroid nodules,there were 3 cases(6.4%)of marginal calcification and 3 cases(6.4%)of crude calcification,which were not significantly different from 3 cases(2.9%)of marginal calcification and 5 cases(4.8%)of crude calcification in benign thyroid nodules(P>0.05).Conclusion:Color Doppler ultrasonography(CDFI)is of high clinical value in differentiating thyroid cancer from benign thyroid lesions,and has the value of being widely popularized and implemented,can improve the disease detection rate.