基于“肾主生殖”理论浅析维生素D缺乏与复发性流产的联系

Relationship Between Vitamin D Deficiency and Recurrent Spontaneous Abortion Based on the Theory of “Kidneydominated Reproduction”

现代研究表明维生素D有免疫调节作用,可促进母胎免疫耐受维持妊娠,补充维生素D可有效防治复发性流产(recurrent spontaneous abortion,RSA)。临床实践中发现维生素D缺乏的表现与中医肾虚证相似,现代药理学研究表明补肾中药及维生素D对RSA的作用有一定的重合性。肾为先天之本,主生殖,中医学中认为RSA多责之于肾,故本文旨在基于"肾主生殖"理论浅析维生素D与RSA的联系,以期为RSA的临床治疗提供新的思路。

Modern studies have shown that vitamin D has immunomodulatory effects,which can promote maternal and fetal immune tolerance to maintain pregnancy,and vitamin D supplementation can effectively prevent and cure recurrent spontaneous abortion (RSA).In clinical practice,it has been found that the manifestations of vitamin D deficiency are similar to the syndrome of kidney deficiency in traditional Chinese medicine.Modern pharmacological studies have shown that there is a certain overlap effect between the effects of kidney tonifying Chinese medicine and vitamin D on RSA.Kidney is the origin of birth,the main reproductive,and Chinese medicine believes that RSA is mostly responsible for kidney,so this paper aims to analyze the relationship between vitamin D and RSA based on the theory of “kidney-dominated reproduction”,in order to provide new ideas for clinical treatment of RSA.