输入性疟疾16例的流行病学特征及全血细胞计数结果分析

Analysis of epidemiological characteristics and complete blood count results of 16 cases of imported malaria

目的分析输入性疟疾流行病学特征及实验室检测结果。方法回顾性收集2017年1月至2020年8月在安徽省铜陵市人民医院就诊的16例输入性疟疾患者临床资料,设为疟疾组,选取30名同期体验人员设为健康对照组。比较两组全血细胞计数及白细胞分类计数。结果16例患者中白细胞计数异常者所占比例为25.0%;红细胞计数降低者所占比例为31.3%;血红蛋白降低者所占比例为37.5%;血细胞比容降低者所占比例43.8%;血小板计数异常者所占比例为93.8%。两组淋巴细胞百分比及绝对值、单核细胞百分比及绝对值及嗜酸粒细胞绝对值比较,差异有统计学有意义(P<0.05或P<0.01)。两组红细胞三项参数和血小板计数比较,差异有高度统计学意义(P<0.01)。结论疟疾感染常明显造成红细胞相关参数的下降,以及血小板计数明显降低,需重点关注。

Objective To analyze the epidemiological characteristics of imported malaria and laboratory test results.Methods The clinical data of 16 imported malaria patients who were treated in Tongling People’s Hospital from January 2017 to August 2020 were retrospectively collected,set as the malaria group,and 30 healthy persons were selected as the healthy control group.The complete blood count and white blood cell differential count between the two groups were compared.Results In 16 patients,the proportion of abnormal white blood cell count was 25.0%;the proportion of people with reduced red blood cell count was 31.3%;the proportion of people with reduced hemoglobin was 37.5%;the proportion of patients with reduced hematocrit was 43.8%;the proportion of abnormal platelet counts was 93.8%.Comparison of the percentage and absolute value of lymphocytes,the percentage and absolute value of monocytes,and the absolute value of eosinophils between the two groups,the differences were statistically significant(P<0.05 or P<0.01).Comparison of three red blood cell parameters and platelet count between the two groups,the differences were highly statistically significant(P<0.01).Conclusion Malaria infection often causes a significant decrease in red blood cell related parameters and a significant decrease in platelet count,which requires special attention.