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猪冠状病毒的起源与遗传演化 被引量:4

Origin and evolution of coronaviruses in pigs
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摘要 冠状病毒变异率高,宿主广泛,主要感染哺乳动物和禽类,严重威胁公共卫生安全与养殖业发展。生猪养殖业中,冠状病毒也是危害猪只健康的重要病原。本研究对4种代表性猪冠状病毒:猪传染性胃肠炎病毒(transmissible gastroenteritis virus, TGEV)、猪流行性腹泻病毒(porcine epidemic diarrhea virus, PEDV)、猪急性腹泻综合征冠状病毒(swine acute diarrhoea syndrome coronavirus, SADS-CoV)和猪δ冠状病毒(porcine delta coronavirus, PDCoV)的起源、流行、遗传演化和跨宿主传播等方面进行综述,为动物冠状病毒的传播、变异和防控研究提供借鉴。 Coronaviruses have a high mutation rate and a wide range of hosts.They mainly infect mammals and birds, posing a serious threat to public health and the development of aquaculture.Coronaviruses are also important pathogens in pig breeding industry.This review summarizes the knowledge on the origin, epidemiology, evolution and potential cross-species transmission of four representative porcine coronaviruses that include transmissible gastroenteritis virus(TGEV),porcine epidemic diarrhea virus(PEDV),swine acute diarrhea syndrome coronavirus(SADS-CoV) and porcine delta coronavirus(PD-CoV),in order to provide a reference for future researches on the transmission, variation and prevention of animal coronaviruses.
作者 吴梓琦 吴少佳 吕华达 罗永文 WU Ziqi;WU Shaojia;LYU Huada;LUO Yongwen(Guangdong Key Laboratory for Prevention and Control of Zoonotic Zoonosis,College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China)
出处 《中国兽医学报》 CAS CSCD 北大核心 2022年第2期376-383,共8页 Chinese Journal of Veterinary Science
基金 “十三五”国家重点研发计划资助项目(2016YFD0500400) 广东省自然科学基金资助项目(2018A030313163)。
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