常用实验动物全身性麻醉药物的使用

General Anesthetics Commonly Used for Laboratory Animals

实验动物全身性麻醉药物多为管制药品,在国内受到严格的监管。经典文献上推荐的多数实验动物全身性麻醉药物,在市面往往购买不到,或者购买时间非常长,以至于在实际的临床应用时可选择的麻醉药物非常有限。加之部分实验动物兽医师对不同种属实验动物全身性麻醉药物的选择和使用缺乏相应的经验,导致目前实验动物全身性麻醉成为限制行业发展的一个重要瓶颈。本文系统总结了市面上常见全身性麻醉药物的属性以及使用注意事项,并在此基础上归纳了常见实验动物种属全身麻醉的注意事项。

General anesthetics used for laboratory animals are mostly controlled drugs,and are subject to strict supervision by the competent government agency in China.Many general anesthetics recommended in the literature are either unavailable or difficult to procure/access in the market,resulting in limited options for clinical use.Furthermore,not all laboratory veterinarians have practical experience in species-specific anesthetic selection and use.Owing to these factors,general anesthesia presents a common institutional challenge in animal surgical programs and serves as a bottleneck that restricts the sustainable development of biomedical industries working with laboratory animal species.This article summarizes the pharmacological properties of common general anesthetics and provides suggestions for general anesthesia in different laboratory animal species.