氯离子响应性纳米纤维素荧光水凝胶的构筑

Fabrication of fluorescent cellulose nanocrystals hydrogels for chloride ion response

为解决传统PVA复合水凝胶制备过程中使用有毒试剂或需要反复多次冻融能耗高、过程繁琐的问题,以植酸(PA)作为交联剂将荧光纳米纤维素(F-CNCs)与聚乙烯醇(PVA)有机结合,基于多重氢键作用,构建了力学性能好、Cl-响应灵敏的PVA/F-CNCs/PA纳米纤维素荧光水凝胶。基于F-CNCs优异的力学性能、荧光性能、良好的生物相容性及纳米效应,分析了PVA水凝胶良好的荧光性能及Cl-响应性。结果表明:当F-CNCs的含量为0.6 g时,PVA/F-CNCs/PA复合水凝胶的压缩强度提高了150%,且结晶度以及热稳定性均有所提高。PVA/F-CNCs/PA复合水凝胶在低的pH值下对Cl-敏感,荧光淬灭效率在Cl-浓度为0~0.2 mol/L范围内呈线性响应,表明制备得到的纳米纤维素荧光水凝胶在Cl-浓度分析检测、疾病诊断、生物和化学传感器等方面具有潜在应用价值。

In order to avoid the usage of toxic reagents and reduce the high energy consumption and complicated multiple freeze-thaw cycles in the traditional preparation process of PVA composite hydrogels,PVA/F-CNCs/PA fluorescent cellulose nanocrystals hydrogels with good mechanical properties and high sensibility to Cl-were prepared by combining fluorescent cellulose nanocrystals(F-CNCs)and poly(vinyl alcohol)(PVA)through multiple hydrogen bonding under the cross-linking of phytic acid(PA).The fluorescent performance and Cl-sensibility of PVA hydrogel were improved significantly due to the excellent mechanical properties,high fluorescent performance,good biocompatibility and nanometer effect of F-CNCs.When the content of F-CNCs was 0.6 g,the compressive strength of PVA/F-CNCs/PA composite hydrogels was increased by 150%,and the crystallinity and thermal stability were also improved.The composite hydrogels were sensitive to Cl-at low pH,and the fluorescence quenching efficiency showed a linear response in the Cl-concentration range of 0-0.2 mol/L.The results indicated that the prepared fluorescent hydrogels had potential application in the field of Cl-concentration analysis and detection,biological and chemical sensors and disease diagnosis.