席汉综合征伴双侧股骨头缺血性坏死患者1例的药学监护

Pharmacological monitoring on a patient with Sheehan’s syndrome complicated with bilateral ischemic necrosis of the femoral head

本研究报道临床药师参与1例席汉综合征合并双侧股骨头缺血性坏死患者入院行髋关节置换手术的治疗,通过对患者激素替代治疗与围手术期镇痛治疗进行分析与药学监护,使治疗方案得以优化,药物使用更合理,同时协助医师选择围手术期预防用抗菌药物与镇痛药物,提出不良反应的防治建议,最终患者得以顺利开展手术,经手术治疗后,患者髋部疼痛明显缓解,治疗有效、合理。临床药师在整个治疗中根据最新的循证医学证据,对席汉综合征患者围手术期进行药学监护,对于患者的用药安全和医生的治疗策略具有重要意义。

This paper reports that clinical pharmacists participated in the treatment of a patient with Sheehan’s syndrome complicated with bilateral ischemic necrosis of the femoral head who was admitted to the hospital for hip replacement.The hormone replacement therapy and perioperative analgesia treatment for the patient were analyzed and pharmacologically monitored to optimize the treatment regimen and rationalize the use of medicine.Meanwhile,the above analysis and pharmacological monitoring enabled physicians to select reasonable antibiotics and analgesics in the perioperative period and propose prevention and treatment suggestions for adverse reactions,and then the surgery was performed smoothly.After the surgery,the patient’s hip pain was obviously relieved,indicating that the treatment was effective and reasonable.The pharmacological monitoring on patients with Sheehan’s syndrome conducted by clinical pharmacists during the whole course of treatment based on the latest evidence-based medical evidence is of significance for the safety of patients’medication and physicians’treatment strategies.