宫腹腔镜联合辅助生殖技术治疗输卵管性不孕患者的临床疗效及安全性

Clinical efficacy and safety of hysteroscopy combined with assisted reproductive technology in the treatment of tubal infertility patients

目的研究对输卵管性不孕患者实施宫腹腔镜联合辅助生殖技术治疗的临床价值。方法36例输卵管性不孕患者,遵从“平衡序贯法”分为对照组(16例)和观察组(20例)。对照组采用常规宫腹腔镜手术治疗,观察组采用宫腹腔镜联合辅助生殖技术治疗。比较两组输卵管再通率,治疗后不同时间段的妊娠率,治疗后性生活质量评分,并发症发生率。结果观察组输卵管再通率95.00%高于对照组的62.50%,差异具有统计学意义(P<0.05)。观察组治疗后1年妊娠率45.00%高于对照组的12.50%,差异具有统计学意义(P<0.05);两组治疗后1.5、2年妊娠率比较,差异无统计学意义(P>0.05)。治疗后,观察组患者的阴道功能、性生活困扰、性活跃度、性生活愉悦感评分分别为(10.32±1.51)、(1.39±0.55)、(1.47±0.45)、(1.89±0.23)分,均高于对照组的(7.21±1.25)、(1.05±0.22)、(1.01±0.25)、(1.01±0.15)分,差异具有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。结论输卵管性不孕患者采用宫腹腔镜联合辅助生殖技术治疗,可有效提升患者输卵管再通率,降低并发症发生率。

Objective To study the clinical value of hysteroscopy combined with assisted reproductive technology in the treatment of tubal infertility patients.Methods A total of 36 patients with tubal infertility were divided into control group(16 cases)and observation group(20 cases)in accordance with the"balance sequential method".The control group was treated with conventional hysteroscopic surgery,and the observation group was treated with hysteroscopy in combination with assisted reproductive technology.Both groups were compared in terms of fallopian tube recanalization rate,pregnancy rate at different time periods after treatment,quality of sexual life score after treatment,and complication rates.Results The fallopian tube recanalization rate of the observation group was 95.00%,which was higher than 62.50% of the control group,and the difference was statistically significant(P<0.05).The pregnancy rate of the observation group 1 year after treatment was 45.00%,which was higher than 12.50% of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in pregnancy rates between the two groups at 1.5 and 2 years after treatment(P>0.05).After treatment,the scores of vaginal function,sexual disturbance,sexual activity,and sexual pleasure of the observation group were(10.32±1.51),(1.39±0.55),(1.47±0.45),and(1.89±0.23)points,which were all higher than(7.21±1.25),(1.05±0.22),(1.01±0.25),and(1.01±0.15)points of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in complication rates between the two groups(P>0.05).Conclusion For patients with tubal infertility,hysteroscopy combined with assisted reproductive technology can effectively increase the rate of tubal recanalization and reduce the complication rates.