黄芪汤加减治疗急性加重期慢性阻塞性肺疾病的疗效分析

The effect of the Huangqi decoction on acute exacerbation of chronic obstructive pulmonary disease

目的:分析黄芪汤加减治疗急性加重期慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)的临床疗效。方法:纳入2019年3月-2020年10月102例患者,分两组(各51例),对照组为常规治疗,试验组为黄芪汤加减治疗,比较两组治疗有效率、肺功能变化、血清C反应蛋白(C-Reactive Protein,CRP)、血清降钙素原(Procalcitonin,PCT)水平。结果:试验组治疗有效率高于对照组(P<0.05);治疗前两组肺功能和CRP、PCT水平无差异性(P>0.05);治疗后试验组1 s用力呼气肺容积(Forced Expiratory Volume in 1 second,FEV1)、用力肺活量(Forced Vital Capacity,FVC)、6 min步行试验(6 Minutes Walk Test,6 MWT)高于对照组,CRP、PCT低于对照组(P<0.05)。结论:黄芪汤加减治疗对于急性加重期慢性阻塞性肺疾病患者的效果显著,值得临床推广。

Objective:To analyze the clinical effect of the Huangqi decoction(黄芪汤)in the treatment of acute exacerbation of chronic obstructive pulmonary disease.Methods:102 patients from March 2019 to October 2020 were selected and divided into two groups(51 cases in each group).The control group was treated with routine treatment,and the experimental group was treated with the Huangqi decoction.The effective rate,lung function changes,CRP and PCT levels in the two groups were compared.Results:The effective rate in the experimental group was higher than the control group(P<0.05);before treatment,there was no difference in lung function,CRP and PCT levels between the two groups(P>0.05);after treatment,FEV,FVC and 6 MWT in the experimental group were higher than the control group,CRP and PCT levels in the experimental group were lower than the control group(P<0.05).Conclusion:The effect of the Huangqi decoction on patients with acute exacerbation of chronic obstructive pulmonary disease is significant,which is worthy of clinical promotion.