重度妊娠高血压病对早产儿白细胞及凝血功能的影响评价

Evaluation of the Influence of Severe Pregnancy-Induced Hypertension on White Blood Cell and Coagulation Function in Premature Infants

目的:评价重度妊娠高血压病对早产儿白细胞及凝血功能的影响。方法:研究开展于2017年1月到2020年6月,抽取80例对象,均为早产儿,其中40例为健康母亲分娩,纳入到对照组,另外40例为重度妊娠高血压病母亲分娩,纳入到实验组。比照两组早产儿的白血胞与凝血功能。结果:两组早产儿的白细胞指标(中性粒细胞绝对数与白细胞总数)及纤维蛋白原进行对比,提示实验组均更低;两组早产儿的部分活化凝血酶原时间、凝血酶原时间及血浆凝血酶时间进行对比,提示实验组均更高;均有很大差异(P<0.05)。结论:相比于健康母亲分娩的早产儿,重度妊娠高血压病母亲分娩的早产儿的白血胞水平与凝血功能均更差,更容易发生凝血功能障碍、出血、感染等疾病,影响其身体健康及生长发育。

Objective:To evaluate the effect of Severe pregnancy-induced hypertension on white blood cell and coagulation function in premature infants.Methods:The study was carried out from January 2017 to June 2020.80 subjects were selected,all of whom were premature babies.Among them,40 were delivered by healthy mothers and were included in the control group.The other 40 were delivered by mothers with severe hypertension of pregnancy.Included in the experimental group.Compare the white blood cells and coagulation function of the two groups of premature infants.Results:The white blood cell indicators(absolute number of neutrophils and total number of white blood cells)and fibrinogen of the two groups of preterm infants were compared,indicating that the experimental group was lower;the partially activated prothrombin time and prothrombin time of the two preterm infants The comparison with plasma thrombin time indicates that the experimental group is higher;there are big differences(P<0.05).Conclusion:Compared with premature infants delivered by healthy mothers,premature infants delivered by mothers with Severe pregnancy-induced hypertension have poorer white blood cell levels and coagulation function,and are more likely to develop coagulation dysfunction,bleeding,infection and other diseases,which affect their health And growth and development.