经方合用治疗系统性硬化症验案举隅

A case study of classical prescriptions in treating systemic sclerosis

系统性硬化症是一种病因未明的以皮肤广泛纤维化为特征的自身免疫性系统性疾病。典型的皮肤损害分为肿胀期、硬化期和萎缩期,甚则导致内脏器官的纤维化。现代临床治疗主要以血管活性剂、结缔组织形成抑制剂、糖皮质激素、免疫抑制剂和对症治疗为主,并没有特异性的疗效,控制病情的同时,不可避免地会带来一定的不良反应。近年来中医药主要从系统性硬化症的病机出发,在治疗此类疾病方面体现出独特优势。笔者主要从系统性硬化症痰瘀痹阻的病机出发,结合临床所见,强调化痰祛瘀,祛寒贯穿始终,寒去则痹去,痰瘀去则硬肿自除,标本兼治,随症加减,以期为系统性硬化症的诊治提供新思路。

Systemic sclerosis is an autoimmune disease characterized by extensive fibrosis of the skin with unknown etiology.Typical skin lesions can be divided into swelling stage,sclerosing stage and atrophic stage,which even leads to fibrosis of internal organs.Modern clinical treatment is mainly based on vasoactive agents,connective tissue formation inhibitors,glucocorticoids,immunosuppressants and symptomatic treatment,and there is no specific curative effect.While controlling the disease,it will inevitably bring some side effects.In recent years,TCM mainly focuses on the pathogenesis of systemic sclerosis and has shown unique advantages in the treatment of such diseases.Based on the pathogenesis of phlegm and stasis obstruction in systemic sclerosis,combined with clinical observation,the author emphasizes the elimination of phlegm and stasis,eliminating cold,phlegm and stasis to remove the swelling,treating both symptoms and root causes,the treatment is modified based on the disease,the prospect of the paper is to provide new ideas for the diagnosis and treatment of systemic sclerosis.