药物共晶的研究进展

Research Progress of Drug Eutectics

阐述了药物共晶的合成原理、合成方法、药物共晶的性质,介绍了药物共晶方面的一些新观点,着重介绍了药物共晶的合成方法、熔点、溶解度、生物利用度、稳定性和多晶型等方面的研究情况。药物共晶作为一类具有良好物理化学性质的新型固体药物,引起了工业界和学术界越来越多的关注。综述了药物共晶在药物性能方面的改善作用,探究了药物共晶的制备方法和表征技术以及相关的性质。

The synthesis principle,synthesis method,and properties of drug eutectics are described.Some new viewpoints in drug eutectics are introduced.The synthesis method,melting point,solubility,bioavailability,stability and polycrystalline of drug eutectics are focused on.As a new type of solid drug with good physicochemical properties,drug eutectics have attracted more and more attention from industry and academia.The improvement of drug eutectics in terms of drug performance is overviewed,the preparation methods and characterization techniques as well as related properties of drug eutectics.