防眩汤治疗椎动脉型颈椎病临床研究

Clinical Study on Vertigo-Removing Decoction in the Treatment of Cervical Spondylosis of Vertebral Artery Type

目的:观察防眩汤治疗椎动脉型颈椎病的临床疗效。方法:将148例椎动脉型颈椎病患者按照随机数字表法分为对照组72例和治疗组76例。治疗组给予防眩汤治疗,对照组给予盐酸氟桂利嗪胶囊治疗。比较两组患者的临床疗效及治疗前后颈性眩晕症状与功能评估量表(cerical vertigo symptoms and function evaluation scale,ESCV)评分、视觉模拟评分(VAS)、血流动力学指标[椎动脉收缩期血流峰值流速(peak systolic flow velocity,SPV)和阻力指数(resistance index,RI)]变化情况。结果:两组患者治疗后ESCV评分高于本组治疗前,且治疗后治疗组高于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后VAS评分低于本组治疗前,且治疗后治疗组低于对照组,差异具有统计学意义(P<0.05)。两组患者治疗后SPV高于本组治疗前,RI低于本组治疗前,治疗后治疗组SPV高于对照组,RI低于对照组,差异具有统计学意义(P<0.05)。对照组有效率为86.1%,治疗组有效率为93.4%,两组患者有效率比较,差异具有统计学意义(P<0.05)。结论:防眩汤治疗椎动脉型颈椎病,可通过改善脑颈部血流速度、降低血流阻力,从而改善患者临床症状,减轻患者眩晕程度,提高生活质量。

Objective:To observe the clinical curative effect of Vertigo-Removing Decoction on cervical spondylosis of vertebral artery type(CSA).Methods:A total of 148 patients with CSA were randomly divided into the control group with 72 cases and the treatment group with 76 cases.The treatment group was treated with Vertigo-Removing Decoction,while the control group was treated with Flunarizine Hydrochloride Capsules.The clinical efficacy and the changes of cervical vertigo symptoms and function evaluation scale(ESCV),visual analogue scale(VAS),hemodynamic indexes′ peak systolic flow velocity(SPV) and resistance index(RI) were compared between the two groups before and after treatment.Results:The ESCV score of the two groups after treatment was higher than that of the same group before treatment,and the index of the treatment group after treatment was higher than that of the control group,the difference was statistically significant(P<0.05).The VAS score of the two groups after treatment was lower than that of the same group before treatment,and the VAS score of the treatment group after treatment was lower than that of the control group,the difference was statistically significant(P<0.05).After treatment,the SPV of the two groups was higher than that of the same group before treatment,while the RI was lower than that before treatment.After treatment,the SPV of the treatment group was higher than that of the control group,while the RI was lower than that of the control group,and all the differences were statistically significant(P<0.05).The effective rate was 86.1% in the control group and 93.4% in the treatment group.There was significant difference between the two groups(P<0.05).Conclusion:Vertigo-Removing Decoction in the treatment of CSA can improve the clinical symptoms of patients,reduce the degree of vertigo and improve the quality of life by improving the blood flow velocity of brain and neck and reducing the blood flow resistance.