当前国内季节性流感疫苗与新型冠状病毒肺炎疫苗同时接种的思考

Consideration on implementation of co-administration of Seasonal Influenza and COVID-19 vaccines during pandemic in China

流感是一种由流感病毒引起的传染性呼吸道疾病。老年人、婴幼儿和患有基础疾病人群,出现严重临床症状和并发症的风险更高。新型冠状病毒与流感病毒的共同感染和流行可导致新型冠状病毒肺炎的预防、诊断、控制、治疗和康复复杂化。季节性流感疫苗和新型冠状病毒肺炎疫苗在目标人群、接种时间、接种单位都有重叠,虽然目前流感疫苗与新型冠状病毒肺炎疫苗同时接种免疫原性和安全性的相关研究证据不足,但世界卫生组织和一些国家已建议流感灭活疫苗和新型冠状病毒肺炎疫苗同时接种。本文汇总了国内外两种疫苗同时接种的政策和研究进展,同时提出了相应的思考和建议,以期为季节性流感疫苗和新型冠状病毒肺炎疫苗接种策略的制订提供科学支撑。

Influenza is an infectious respiratory disease caused by the influenza viruses.Older people,infants and people with underlying medical conditions could have a higher risk of severe influenza symptoms and complications.The co-infection of Coronavirus Diseases 2019(COVID-19)with influenza viruses could lead to the complication of prevention,diagnosis,control,treatment,and recovery of COVID-19.Influenza vaccine and COVID-19 vaccine overlapped in target populations,vaccination time,and inoculation units.Although there was insufficient evidence on the immunogenicity and safety of co-administration of influenza vaccine and COVID-19 vaccine,World Health Organization and some countries recommended co-administration of inactivated influenza vaccine and COVID-19 vaccine.This review summarized domestic and international vaccination policies and research progress,and put forward corresponding suggestions in order to provide scientific support for the formulation of vaccination strategy on seasonal influenza vaccine and COVID-19 vaccine.