冬凌草化学成分、药理作用及临床应用研究进展

Research progress on chemical constituents, pharmacological effects and clinical application of Rabdosia rubescens

冬凌草为唇形科植物碎米桠Rabdosia rubescens的干燥地上部分。其主要化学成分有单萜、二萜、三萜等萜类化合物,此外还含有挥发油、甾体、黄酮、生物碱、氨基酸、有机酸、单糖等成分。现代药理研究表明冬凌草具有抗肿瘤、抗菌消炎、抗氧化、免疫增强等作用。基于近年来公开发表的文献,对冬凌草的化学成分、主要药理作用进行综合分析,并对临床应用现状进行整理和总结,旨在为冬凌草的深入研究和开发利用提供参考。

Rabdosia rubescens is a dry above-ground part of the Labiatae plant. Its main chemical components are monoterpenes,diterpenes, triterpenes and other terpenes, in addition, it also contains volatile oil, steroids, flavones, alkaloids, amino acids, organic acids, monosaccharides and other components. Modern pharmacological studies have shown that R. rubescent has anti-tumor,anti-bacterial, anti-inflammatory, anti-oxidant, immune enhancement and other effects. Based on the published literatures in recent years, the chemical constituents and main pharmacological effects of R. rubescens were comprehensively analyzed, and the current situation of clinical application was sorted out and summarized, aiming to provide reference for the in-depth research, development and utilization of R. rubescens.